Mechanism of antioxidant properties of quercetin and quercetin-DNA complex

• Published in: Journal of molecular modeling Vol. 26; no. 6; p. 133
• Main Authors: Song, Xiaoli, Wang, Yali, Gao, Liguo
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2020; Springer Nature B.V
• Subjects: Antioxidants; Antioxidants - pharmacology; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Computer Appl. in Life Sciences; Computer Applications in Chemistry; Deoxyribonucleic acid; DNA; DNA - chemistry; Enthalpy; Flavonoids; Free Radical Scavengers - pharmacology; Free radicals; Hydroxyl groups; Molecular docking; Molecular Docking Simulation; Molecular Medicine; Original Paper; Quercetin - chemistry; Quercetin - pharmacology; Scavenging; Theoretical and Computational Chemistry; Thiobarbituric acid; Radical scavenging activity; Fukui functions; BDE; Reactivity indices; DNA; Quercetin

Quercetin is the most abundant flavonoid with potent antioxidant activities. In the current research, the antioxidant properties of quercetin and quercetin-DNA complex were investigated theoretically and experimentally. Free radical scavenging experiments with thiobarbituric acid–reactive substances...