Clinical lactation studies and the role of pharmacokinetic modeling and simulation in predicting drug exposures in breastfed infants

• Published in: Journal of pharmacokinetics and pharmacodynamics Vol. 47; no. 4; pp. 295 - 304
• Main Authors: Anderson, Philip O., Momper, Jeremiah D.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.08.2020; Springer Nature B.V
• Subjects: Biochemistry; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Breast feeding; Breastfeeding & lactation; Infants; Lactation; Medical personnel; Nursing; Pharmacokinetics; Pharmacology/Toxicology; Pharmacy; Review Paper; Veterinary Medicine/Veterinary Science; Human milk; Lactation; Breastfeeding; Pharmacokinetic modeling

The relative lack of information on medication use during breastfeeding is an ongoing problem for health professionals and mothers alike. Most nursing mothers are prescribed some form of medication, yet some mothers either discontinue breastfeeding or avoid medications entirely. Although regulatory...