Altered brain white matter connectome in children and adolescents with prenatal alcohol exposure

• Published in: Brain Structure and Function Vol. 225; no. 3; pp. 1123 - 1133
• Main Authors: Long, Xiangyu, Little, Graham, Treit, Sarah, Beaulieu, Christian, Gong, Gaolang, Lebel, Catherine
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.04.2020; Springer Nature B.V
• Subjects: Adolescent; Adolescents; Biomedical and Life Sciences; Biomedicine; Brain - pathology; Cell Biology; Child; Child, Preschool; Children; Cognitive ability; Connectome; Diffusion Magnetic Resonance Imaging; Ethanol - adverse effects; Female; Humans; Male; Neural networks; Neural Pathways - pathology; Neuroimaging; Neurology; Neurosciences; Original Article; Pregnancy; Prenatal experience; Prenatal exposure; Prenatal Exposure Delayed Effects - pathology; Substantia alba; Teenagers; White Matter - pathology; Graph theory; Prenatal alcohol exposure; Inter-/intra-network; Diffusion tensor imaging; Structural connectome; Global efficiency

Diffuson tensor imaging (DTI) has demonstrated widespread alterations of brain white matter structure in children with prenatal alcohol exposure (PAE), yet it remains unclear how these alterations affect the structural brain network as a whole. The present study aimed to examine changes in the DTI-b...