Intrinsic Fluorescence of Protoporphyrin IX from Blood Samples Can Yield Information on the Growth of Prostate Tumours

• Published in: Journal of fluorescence Vol. 20; no. 6; pp. 1159 - 1165
• Main Authors: de Oliveira Silva, Flávia Rodrigues, Bellini, Maria Helena, Tristão, Vivian Regina, Schor, Nestor, Vieira, Nilson Dias, Courrol, Lilia Coronato
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.11.2010
• Subjects: Analytical Chemistry; Animals; Antigens; Biochemistry; Biological and Medical Physics; Biomarkers, Tumor - blood; Biomedical and Life Sciences; Biomedicine; Biophysics; Biotechnology; Blood; Calibration; Cancer; Diagnosis; Fluorescence; Humans; Male; Mice; Mice, Nude; Original Paper; Porphyrins; Prostate; Prostatic Neoplasms - blood; Prostatic Neoplasms - pathology; Protoporphyrins - blood; Sensitivity and Specificity; Spectrometry, Fluorescence; Tumor Cells, Cultured; Tumours; Tumour stage; Fluorescence; Spectroscopy; Porphyrin; Prostate cancer

Prostate cancer is one of the most common types of cancer in men, and unfortunately many prostate tumours remain asymptomatic until they reach advanced stages. Diagnosis is typically performed through Prostate-Specific Antigen (PSA) quantification, Digital Rectal Examination (DRE) and Transrectal Ul...