Cytoplasmic SQSTM1/ P62 Accumulation Predicates a Poor Prognosis in Patients with Malignant Tumor

• Published in: Journal of Cancer Vol. 9; no. 21; pp. 4072 - 4086
• Main Authors: Zhu, Linhai, Wang, Yiqing, He, Jing, Tang, Jie, Lv, Wang, Hu, Jian
• Format: Journal Article
• Language: English
• Published: Australia Ivyspring International Publisher 01.01.2018
• Subjects: Research Paper; malignant tumor; prognosis; SQSTM1/p62

SQSTM1/p62, as an autophagy marker, is a key molecule involved in the autophagy process. Recent studies have demonstrated that p62 has a close relationship with tumorigenesis and progression, but the impact of p62 on patients' survival has not been comprehensively understood. Therefore, we cond...