The effect of zinc aspartate pretreatment on ischemia-reperfusion injury and early changes of blood and tissue antioxidant enzyme activities after unilateral testicular torsion-detorsion

• Published in: Journal of pediatric surgery Vol. 39; no. 1; pp. 91 - 95
• Main Authors: ÖZKAN, Y. K. U, BORAN, C, KILINC, M, GARIPARDIC, M, KURUTAS, E. B
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Elsevier Inc 2004; Elsevier
• Subjects: Animals; Antioxidants - metabolism; Aspartic Acid - analogs & derivatives; Aspartic Acid - pharmacology; Aspartic Acid - therapeutic use; Biological and medical sciences; Catalase - blood; Catalase - metabolism; Disease Models, Animal; General aspects; Gynecology. Andrology. Obstetrics; ischemia-reperfusion; Male; Male genital diseases; Malondialdehyde - blood; Malondialdehyde - metabolism; Medical sciences; Non tumoral diseases; Rats; Rats, Sprague-Dawley; Reperfusion Injury - enzymology; Reperfusion Injury - etiology; Reperfusion Injury - prevention & control; Spermatic Cord Torsion - complications; Spermatic Cord Torsion - drug therapy; Spermatic Cord Torsion - enzymology; Superoxide Dismutase - blood; Superoxide Dismutase - metabolism; testicular torsion; Testis - drug effects; Testis - enzymology; Testis - pathology; Zinc aspartate; Zinc aspartate; testicular torsion; ischemia-reperfusion; Pediatrics; Nervous system diseases; Injury; Cardiovascular disease; Aspartate; Change; Antioxidant; Blood; Zinc; Vascular disease; Medicine; Spermatic cord diseases; Tissue; Reperfusion; Enzymatic activity; Ischemia; Excitatory aminoacid; Neurotransmitter; Unilateral; Spermatic cord torsion; Early; Lesion; Pretreatment; Male genital diseases

The aim of this study is to investigate the effect of zinc aspartate (ZA) pretreatment on ischemia-reperfusion (I/R) injury and blood and tissue antioxidant enzyme activity early after unilateral testicular torsion-detorsion (T/D). Forty prepubertal male Sprague-Dawley rats (weight 160 to 220 g) wer...