Brief Report: A Double-Blind, Placebo-Controlled, Crossover, Proof-of-Concept Study of Minocycline in Autism Spectrum Disorder - Erickson, Craig A.; Shaffer, Rebecca C.; Will, Meredith; Schmitt, Lauren M.; Horn, Paul; Hirst, Kathy; Pedapati, Ernest V.; Ober, Nicole; Tumuluru, Rameshwari V.; Handen, Benjamin L.; Beversdorf, David Q. (Journal of autism and developmental disorders, 2025)
Keywords: Adolescent; Age; Anatomy; Animal models; Animals; Anti-Bacterial Agents - therapeutic use; Anti-inflammatory agents; Antibiotics; Anxiety; Autism; Autism Spectrum Disorder - drug therapy; Autism Spectrum Disorders; Behavior; Behavior Problems; Behavior Rating Scales; Behavioral Science and Psychology; Brain; Brief Report; Caregivers; Check Lists; Child; Child and School Psychology; Children & youth; Clinical trials; Cross-Over Studies; Cytokines; Daily Living Skills; Developmental Disabilities; Double-Blind Method; Exhibits; Female; Gelatinase B; Hormones; Humans; Inflammation; Interpersonal Relationship; Laboratory Safety; Least Squares Statistics; Male; Matrix metalloproteinase; Medical Evaluation; Metalloproteinase; Minocycline; Minocycline - therapeutic use; Neurosciences; Outcome Measures; Outcomes of Treatment; Oxidative stress; Pathophysiology; Pediatrics; Phenotypes; Physical Examinations; Physicians; Pilot projects; Placebos; Proof of Concept Study; Psychology; Public Health; Social Behavior; Social interaction; Tetracycline; Treatment Outcome; Young Adult; Youth; Minocycline; Autism; Clinical trial; Autism spectrum disorder