Backward masking in mice requires visual cortex

• Published in: Nature neuroscience Vol. 27; no. 1; pp. 129 - 136
• Main Authors: Gale, Samuel D., Strawder, Chelsea, Bennett, Corbett, Mihalas, Stefan, Koch, Christof, Olsen, Shawn R.
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.01.2024; Nature Publishing Group
• Subjects: 631/378/2613; 631/378/3917; 64/60; Accuracy; Animal Genetics and Genomics; Behavior; Behavioral Sciences; Biological Techniques; Biomedical and Life Sciences; Biomedicine; Circuits; Genetics; Human behavior; Human subjects; Information processing; Masking; Neurobiology; Neurosciences; Optics; Performance degradation; Response rates; Target masking; Visual cortex; Visual tasks

Visual masking can reveal the timescale of perception, but the underlying circuit mechanisms are not understood. Here we describe a backward masking task in mice and humans in which the location of a stimulus is potently masked. Humans report reduced subjective visibility that tracks behavioral defi...