Elevated serum levels of interleukin-10 in adult-onset Still’s disease are associated with disease activity

• Published in: Clinical rheumatology Vol. 38; no. 11; pp. 3205 - 3210
• Main Authors: Sun, Yue, Wang, Zhihong, Chi, Huihui, Hu, Qiongyi, Ye, Junna, Liu, Honglei, Cheng, Xiaobing, Shi, Hui, Zhou, Zhuochao, Teng, Jialin, Yang, Chengde, Su, Yutong
• Format: Journal Article
• Language: English
• Published: London Springer London 01.11.2019; Springer Nature B.V
• Subjects: Adult; Arthralgia; Brief Report; C-reactive protein; Case-Control Studies; China - epidemiology; Cytokines; Erythrocyte sedimentation rate; Female; Ferritin; Fever; Humans; IL-1β; Inflammatory diseases; Interleukin 10; Interleukin 18; Interleukin 6; Interleukin-10 - blood; Lymphadenopathy; Male; Medicine; Medicine & Public Health; Middle Aged; Pharyngitis; Pharynx; Rheumatology; Serum levels; Splenomegaly; Still's Disease, Adult-Onset - blood; Still's Disease, Adult-Onset - epidemiology; Tumor necrosis factor-α; Young Adult; China; Inflammation; Disease activity; Adult-onset Still’s disease; IL-10

To evaluate the serum levels of the anti-inflammatory cytokine interleukin-10 (IL-10) in patients with adult-onset Still’s disease (AOSD), a rare, systemic, and multigenic inflammatory disease. The serum levels of IL-10, IL-1β, IL-6, IL-18, and TNF-α were examined by electrochemiluminescence assay....