Cell proliferation, apoptosis, and angiogenesis in non-functional pituitary adenoma: association with tumor invasiveness

• Published in: Endocrine Vol. 69; no. 3; pp. 596 - 603
• Main Authors: Ghadir, Maliheh, Khamseh, Mohammad E., Panahi-shamsabad, Mahshid, Ghorbani, Mohammad, Akbari, Hamideh, Mehrjardi, Ali Zare, Honardoost, Maryam, Jafar-Mohammadi, Bahram
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.09.2020; Springer Nature B.V
• Subjects: Adenoma; Angiogenesis; Apoptosis; Bcl-2 protein; CD105 antigen; CD34 antigen; Cell growth; Cell proliferation; Diabetes; Endocrinology; Endostatin; Fibroblast growth factor 2; Humanities and Social Sciences; Internal Medicine; Invasiveness; Magnetic resonance imaging; Medicine; Medicine & Public Health; Microvasculature; multidisciplinary; Original Article; p53 Protein; Pituitary; Science; Tumors; Vascular endothelial growth factor; Angiogenesis; Proliferation; Tumor invasiveness; Nonfunctional pituitary adenoma; Apoptosis

Purpose Non-functioning pituitary adenoma (NFPA) is the most prevalent pituitary macroadenoma. No prognostic marker has been found to explain the behavior of these tumors. We aimed to explore cell proliferation, apoptosis, proangiogenic markers, and microvascular density (MVD) in noninvasive and inv...