Akkermansia muciniphila: biology, microbial ecology, host interactions and therapeutic potential

• Published in: Nature reviews. Microbiology Vol. 23; no. 3; pp. 162 - 177
• Main Authors: Ioannou, Athanasia, Berkhout, Maryse D., Geerlings, Sharon Y., Belzer, Clara
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.03.2025; Nature Publishing Group
• Subjects: 631/326/2565/2134; 631/326/41/1969; 692/4020/2741/2135; Akkermansia - classification; Akkermansia - genetics; Akkermansia - physiology; Akkermansia muciniphila; Animals; Bacteria; Biomarkers; Biomedical and Life Sciences; Ecological effects; Ecology; Ecophysiology; Gastrointestinal Microbiome - physiology; Host Microbial Interactions; Human performance; Humans; Infectious Diseases; Intestinal microflora; Intestinal Mucosa - microbiology; Life Sciences; Medical Microbiology; Microbiology; Microbiomes; Microbiota; Microorganisms; Mucins - metabolism; Parasitology; Phylogeny; Probiotics; Probiotics - therapeutic use; Review Article; Therapeutic applications; Verrucomicrobia - classification; Verrucomicrobia - genetics; Verrucomicrobia - physiology; Virology

Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic applications. The discovery of A. muciniphila as an important member of our gut microbiome, occupying an extraordinary niche in the human gut, ha...