Akkermansia muciniphila: biology, microbial ecology, host interactions and therapeutic potential
Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic applications. The discovery of A. muciniphila as an important member of our gut microbiome, occupying an extraordinary niche in the human gut, ha...
Saved in:
| Published in | Nature reviews. Microbiology Vol. 23; no. 3; pp. 162 - 177 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
London
Nature Publishing Group UK
01.03.2025
Nature Publishing Group |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Akkermansia muciniphila
is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic applications. The discovery of
A. muciniphila
as an important member of our gut microbiome, occupying an extraordinary niche in the human gut, has led to new hypotheses on gut health, beneficial microorganisms and host–microbiota interactions. This microorganism has established a unique position in human microbiome research, similar to its role in the gut ecosystem. Its unique traits in using mucin sugars and mechanisms of action that can modify host health have made
A. muciniphila
a subject of enormous attention from multiple research fields.
A. muciniphila
is becoming a model organism studied for its ability to modulate human health and gut microbiome structure, leading to commercial products, a genetic model and possible probiotic formulations. This Review provides an overview of
A. muciniphila
and
Akkermansia
genus phylogeny, ecophysiology and diversity. Furthermore, the Review discusses perspectives on ecology, strategies for harnessing beneficial effects of
A. muciniphila
for human mucosal metabolic and gut health, and its potential as a biomarker for diagnostics and prognostics.
In this Review, Belzer and colleagues explore the diversity of the gut bacterium
Akkermansia muciniphila
, its biological functions and interactions with the host, diet and other members of the microbiota, as well as its association with health and disease and its potential in various applications. |
|---|---|
| AbstractList | Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic applications. The discovery of A. muciniphila as an important member of our gut microbiome, occupying an extraordinary niche in the human gut, has led to new hypotheses on gut health, beneficial microorganisms and host-microbiota interactions. This microorganism has established a unique position in human microbiome research, similar to its role in the gut ecosystem. Its unique traits in using mucin sugars and mechanisms of action that can modify host health have made A. muciniphila a subject of enormous attention from multiple research fields. A. muciniphila is becoming a model organism studied for its ability to modulate human health and gut microbiome structure, leading to commercial products, a genetic model and possible probiotic formulations. This Review provides an overview of A. muciniphila and Akkermansia genus phylogeny, ecophysiology and diversity. Furthermore, the Review discusses perspectives on ecology, strategies for harnessing beneficial effects of A. muciniphila for human mucosal metabolic and gut health, and its potential as a biomarker for diagnostics and prognostics.Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic applications. The discovery of A. muciniphila as an important member of our gut microbiome, occupying an extraordinary niche in the human gut, has led to new hypotheses on gut health, beneficial microorganisms and host-microbiota interactions. This microorganism has established a unique position in human microbiome research, similar to its role in the gut ecosystem. Its unique traits in using mucin sugars and mechanisms of action that can modify host health have made A. muciniphila a subject of enormous attention from multiple research fields. A. muciniphila is becoming a model organism studied for its ability to modulate human health and gut microbiome structure, leading to commercial products, a genetic model and possible probiotic formulations. This Review provides an overview of A. muciniphila and Akkermansia genus phylogeny, ecophysiology and diversity. Furthermore, the Review discusses perspectives on ecology, strategies for harnessing beneficial effects of A. muciniphila for human mucosal metabolic and gut health, and its potential as a biomarker for diagnostics and prognostics. Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic applications. The discovery of A. muciniphila as an important member of our gut microbiome, occupying an extraordinary niche in the human gut, has led to new hypotheses on gut health, beneficial microorganisms and host–microbiota interactions. This microorganism has established a unique position in human microbiome research, similar to its role in the gut ecosystem. Its unique traits in using mucin sugars and mechanisms of action that can modify host health have made A. muciniphila a subject of enormous attention from multiple research fields. A. muciniphila is becoming a model organism studied for its ability to modulate human health and gut microbiome structure, leading to commercial products, a genetic model and possible probiotic formulations. This Review provides an overview of A. muciniphila and Akkermansia genus phylogeny, ecophysiology and diversity. Furthermore, the Review discusses perspectives on ecology, strategies for harnessing beneficial effects of A. muciniphila for human mucosal metabolic and gut health, and its potential as a biomarker for diagnostics and prognostics.In this Review, Belzer and colleagues explore the diversity of the gut bacterium Akkermansia muciniphila, its biological functions and interactions with the host, diet and other members of the microbiota, as well as its association with health and disease and its potential in various applications. Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic applications. The discovery of A. muciniphila as an important member of our gut microbiome, occupying an extraordinary niche in the human gut, has led to new hypotheses on gut health, beneficial microorganisms and host–microbiota interactions. This microorganism has established a unique position in human microbiome research, similar to its role in the gut ecosystem. Its unique traits in using mucin sugars and mechanisms of action that can modify host health have made A. muciniphila a subject of enormous attention from multiple research fields. A. muciniphila is becoming a model organism studied for its ability to modulate human health and gut microbiome structure, leading to commercial products, a genetic model and possible probiotic formulations. This Review provides an overview of A. muciniphila and Akkermansia genus phylogeny, ecophysiology and diversity. Furthermore, the Review discusses perspectives on ecology, strategies for harnessing beneficial effects of A. muciniphila for human mucosal metabolic and gut health, and its potential as a biomarker for diagnostics and prognostics. In this Review, Belzer and colleagues explore the diversity of the gut bacterium Akkermansia muciniphila , its biological functions and interactions with the host, diet and other members of the microbiota, as well as its association with health and disease and its potential in various applications. Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic applications. The discovery of A. muciniphila as an important member of our gut microbiome, occupying an extraordinary niche in the human gut, has led to new hypotheses on gut health, beneficial microorganisms and host-microbiota interactions. This microorganism has established a unique position in human microbiome research, similar to its role in the gut ecosystem. Its unique traits in using mucin sugars and mechanisms of action that can modify host health have made A. muciniphila a subject of enormous attention from multiple research fields. A. muciniphila is becoming a model organism studied for its ability to modulate human health and gut microbiome structure, leading to commercial products, a genetic model and possible probiotic formulations. This Review provides an overview of A. muciniphila and Akkermansia genus phylogeny, ecophysiology and diversity. Furthermore, the Review discusses perspectives on ecology, strategies for harnessing beneficial effects of A. muciniphila for human mucosal metabolic and gut health, and its potential as a biomarker for diagnostics and prognostics. |
| Author | Geerlings, Sharon Y. Berkhout, Maryse D. Belzer, Clara Ioannou, Athanasia |
| Author_xml | – sequence: 1 givenname: Athanasia surname: Ioannou fullname: Ioannou, Athanasia organization: Laboratory of Microbiology, Wageningen University and Research – sequence: 2 givenname: Maryse D. orcidid: 0000-0003-3765-8853 surname: Berkhout fullname: Berkhout, Maryse D. organization: Laboratory of Microbiology, Wageningen University and Research – sequence: 3 givenname: Sharon Y. surname: Geerlings fullname: Geerlings, Sharon Y. organization: Laboratory of Microbiology, Wageningen University and Research – sequence: 4 givenname: Clara orcidid: 0000-0001-6922-836X surname: Belzer fullname: Belzer, Clara email: clara.belzer@wur.nl organization: Laboratory of Microbiology, Wageningen University and Research |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/39406893$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kUtP3TAQRi1Exav9AyxQpG66aFo7tmO7uyvUl4TUTbt2J8mEa0jsYDsL_j2m90IlFqz80Dkzo_lOyaEPHgk5Z_QTo1x_ToJJZWraiJoyRtuaHZATpgStmeTi8PnetMfkNKUbShspVXNEjrkRtNWGn5C_m9tbjDP45KCa1955t2zdBF-qzoUpXN9_rGbXx9A5mCrs91_bkHLlfMYIfXbBpwr8UOVteS-4ZtdXS8joc5HekjcjTAnf7c8z8ufb19-XP-qrX99_Xm6u6p4rmWsDVGNrtKEclDLDABSH0YzQcdlI1IOUTEtpTAeDQOxGoJx2SouODYIC52fkw67uEsPdiinb2aUepwk8hjVZzpiiqlFSF_T9C_QmrNGX6QrVlu5GtE2hLvbU2s042CW6GeK9fdpdAfQOKOtJKeJoe5fhcR05gpsso_YxJruLyZaY7L-YLCtq80J9qv6qxHdSKrC_xvh_7FesBwfFpSA |
| CitedBy_id | crossref_primary_10_1002_adfm_202421680 crossref_primary_10_3389_fimmu_2025_1536694 crossref_primary_10_3389_fmicb_2025_1536778 crossref_primary_10_3390_biology14030316 crossref_primary_10_1016_j_ijbiomac_2025_140994 crossref_primary_10_1186_s40104_025_01183_z crossref_primary_10_3389_fmicb_2024_1500886 |
| Cites_doi | 10.15252/emmm.202217241 10.1038/s41564-024-01663-4 10.1128/AEM.01487-21 10.1002/advs.202100536 10.1038/nm.4236 10.3389/fcimb.2019.00239 10.3390/microorganisms10081605 10.1152/ajpregu.00387.2012 10.1111/jth.14861 10.1038/s41591-019-0495-2 10.2337/db11-0227 10.1128/AEM.03004-19 10.1146/annurev-physiol-031522-092054 10.1128/IAI.72.11.6446-6454.2004 10.1007/s00253-021-11622-2 10.1002/pmic.202100125 10.1016/j.foodres.2017.09.004 10.1097/CM9.0000000000000696 10.1038/ismej.2012.6 10.1128/AEM.00692-09 10.1128/AEM.04050-14 10.1038/s41396-022-01255-2 10.1038/s41586-022-04985-7 10.1016/j.cub.2016.04.016 10.3390/nu14122436 10.1016/j.chom.2023.10.016 10.1159/000443360 10.1016/j.bpg.2017.10.001 10.1101/2024.03.27.586211 10.3920/BM2016.0185 10.1038/s41598-024-53430-4 10.1186/s12866-021-02360-6 10.1073/pnas.1115621109 10.1111/jcpp.13409 10.1073/pnas.0906412106 10.3389/fnut.2021.689456 10.1186/s12864-017-4195-3 10.1038/s41467-024-48770-8 10.3389/fmicb.2016.01157 10.1136/gutjnl-2014-308778 10.1172/JCI17129 10.1007/s11596-021-2464-5 10.1016/j.foodres.2021.110648 10.1128/AEM.01014-17 10.1038/s41467-023-37533-6 10.1038/s41586-019-1058-x 10.3390/ijms21082668 10.1007/s10482-018-1040-x 10.3390/nu15081815 10.3390/microorganisms6030075 10.1038/s41575-022-00631-9 10.1128/AEM.01641-16 10.1038/s41564-023-01464-1 10.1126/science.aaw7479 10.1194/jlr.R054114 10.1038/nature09944 10.1186/s12915-017-0454-7 10.1128/AEM.01477-07 10.3390/ijms24010045 10.1002/ana.26084 10.1371/journal.pbio.1002533 10.4161/gmic.1.4.12778 10.1186/s13059-021-02427-7 10.1126/scitranslmed.aad7121 10.1128/mBio.00770-17 10.1128/mBio.01438-14 10.1007/s00018-018-2943-4 10.1073/pnas.1219451110 10.3389/fmicb.2021.632454 10.1503/cmaj.121189 10.1155/2022/3845104 10.1099/ijsem.0.001399 10.1371/journal.pone.0146144 10.4014/jmb.1811.11023 10.1099/ijs.0.02873-0 10.1016/j.bpg.2013.03.001 10.3389/fgene.2015.00081 10.1101/gr.216242.116 10.1016/j.micpath.2016.02.005 10.1530/JME-16-0054 10.3748/wjg.v21.i29.8787 10.1038/nri1391 10.1038/s41467-023-37324-z 10.1038/s42003-024-05867-6 10.1093/nar/gkt1178 10.1186/s12979-019-0145-z 10.1007/s00253-020-10976-3 10.1152/ajpendo.00140.2019 10.1038/s41366-018-0201-3 10.1371/journal.pone.0173004 10.1038/srep16643 10.1016/j.tim.2020.02.003 10.1099/jmm.0.001435 10.1038/ismej.2010.71 10.1111/j.1753-4887.2011.00388.x 10.1128/AEM.02117-19 10.1038/s41598-020-58863-1 10.1111/jam.13022 10.1038/s41598-022-25873-0 10.1080/19490976.2021.1892441 10.1016/j.jnutbio.2011.10.003 10.1016/j.phymed.2023.155249 10.1038/s41467-020-17075-x 10.1053/j.gastro.2007.02.056 10.1128/aem.01121-23 10.1016/j.jbc.2022.102439 10.1128/CMR.00338-20 10.1126/science.1155725 10.1038/s41387-020-0115-8 10.1016/j.chom.2015.04.004 10.1128/AEM.00908-08 10.1126/scitranslmed.aaf2311 10.3390/cells11132084 10.1371/journal.pone.0016952 10.4014/jmb.1410.10014 10.1371/journal.pone.0076520 10.1038/s41522-022-00366-0 10.1128/mBio.00478-21 10.1007/s12035-023-03602-6 10.1016/j.jcmgh.2023.12.003 10.1038/s41564-023-01407-w 10.1038/s41598-020-71113-8 10.1016/j.bbrc.2021.02.022 10.1080/19490976.2023.2208504 10.1016/j.anaerobe.2019.102135 10.1371/journal.pone.0140301 10.1038/s41380-022-01569-9 10.1136/gutjnl-2021-326835 10.1016/j.cell.2018.04.027 10.3389/fmicb.2024.1354447 10.1152/ajpgi.00202.2016 10.1016/j.bbadis.2020.165765 10.1016/j.ijbiomac.2020.01.246 10.1038/ncomms13329 10.3390/nu11081943 10.1016/j.chom.2023.05.007 10.1136/gutjnl-2014-307142 10.1016/j.anaerobe.2019.102138 10.1016/j.bbamcr.2023.119630 10.1038/s41564-021-00880-5 10.1017/S0007114510000176 10.1038/s41467-024-47275-8 10.1007/s12094-024-03493-6 10.1016/j.freeradbiomed.2012.10.554 10.15252/msb.20188486 10.1128/iai.60.10.3971-3978.1992 10.1038/s44320-024-00036-7 10.1016/j.cell.2014.09.053 10.1038/s41467-020-18696-y 10.3389/fimmu.2019.00277 10.1016/j.jbc.2022.101917 10.1136/gutjnl-2019-320105 10.1053/j.gastro.2009.03.007 10.1016/j.vetmic.2013.05.009 10.3390/ijms24043817 10.1016/j.tim.2023.07.012 10.7717/peerj.10941 10.3390/ijms21010072 10.1099/ijsem.0.005697 10.1016/j.cell.2013.12.016 10.3389/fmicb.2017.01804 10.1007/s00394-012-0479-1 10.1128/AEM.01226-07 10.1038/s41586-019-1443-5 10.1111/1751-7915.13033 10.3389/fcimb.2022.957439 10.3389/fcimb.2021.698914 10.1038/s41564-023-01366-2 10.1093/glycob/cwac027 10.1016/j.heliyon.2024.e27527 10.1111/j.1399-302X.2007.00335.x 10.1038/s41598-019-51878-3 10.1016/j.tim.2022.08.003 10.2337/db14-1916 10.1371/journal.pone.0157607 10.3389/fmicb.2023.1098386 10.3390/antiox10122001 10.1016/j.carres.2015.08.001 10.1016/j.phrs.2020.105174 10.3389/fimmu.2020.596103 10.1128/AEM.00342-14 10.1093/glycob/cwab105 10.1016/j.tim.2021.06.003 10.1128/jb.00334-23 10.1371/journal.pone.0010667 10.1016/j.celrep.2016.01.026 10.1038/s41440-024-01627-5 10.3390/antiox13030304 10.1016/j.anaerobe.2016.10.011 10.1126/scitranslmed.abb0322 10.1002/mbo3.796 10.1136/gutjnl-2023-329996 10.1136/gutjnl-2012-303839 10.3389/fimmu.2022.946248 10.1371/journal.pone.0016876 10.3390/jpm12091479 10.1038/emm.2017.282 10.3389/fmicb.2023.1238580 10.1038/s41467-020-17847-5 10.1128/msystems.00294-24 10.1073/pnas.2012196117 10.1111/jgh.13278 10.1016/j.cell.2016.10.043 10.1021/acs.analchem.8b01834 10.3390/brainsci14030238 10.1016/j.alit.2022.02.004 10.1182/bloodadvances.2016002121 |
| ContentType | Journal Article |
| Copyright | Springer Nature Limited 2024 Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. 2024. Springer Nature Limited. Copyright Nature Publishing Group Mar 2025 |
| Copyright_xml | – notice: Springer Nature Limited 2024 Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. – notice: 2024. Springer Nature Limited. – notice: Copyright Nature Publishing Group Mar 2025 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7QL 7U9 8FD C1K FR3 H94 K9. M7N NAPCQ P64 RC3 7X8 |
| DOI | 10.1038/s41579-024-01106-1 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Bacteriology Abstracts (Microbiology B) Virology and AIDS Abstracts Technology Research Database Environmental Sciences and Pollution Management Engineering Research Database AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Algology Mycology and Protozoology Abstracts (Microbiology C) Nursing & Allied Health Premium Biotechnology and BioEngineering Abstracts Genetics Abstracts MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Nursing & Allied Health Premium Genetics Abstracts Virology and AIDS Abstracts Technology Research Database Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Engineering Research Database Biotechnology and BioEngineering Abstracts Environmental Sciences and Pollution Management MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic Nursing & Allied Health Premium MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology Ecology |
| EISSN | 1740-1534 |
| EndPage | 177 |
| ExternalDocumentID | 39406893 10_1038_s41579_024_01106_1 |
| Genre | Journal Article Review |
| GroupedDBID | --- .55 0R~ 123 29M 36B 39C 3V. 4.4 53G 70F 7RV 7X7 88A 88E 88I 8AO 8C1 8CJ 8FE 8FH 8FI 8FJ 8R4 8R5 AAEEF AARCD AAWYQ AAYZH AAZLF ABAWZ ABDBF ABJNI ABLJU ABUWG ACGFO ACGFS ACMJI ACPRK ACUHS ADBBV ADFRT AENEX AEUYN AFBBN AFKRA AFRAH AFSHS AGAYW AGHTU AHBCP AHMBA AHOSX AHSBF AIBTJ ALFFA ALIPV ALMA_UNASSIGNED_HOLDINGS AMTXH ARMCB ASPBG AVWKF AXYYD AZFZN AZQEC BBNVY BENPR BHPHI BKEYQ BKKNO BKSAR BPHCQ BVXVI CCPQU CS3 D1J DB5 DU5 DWQXO EAD EAP EAS EBS EE. EJD EMB EMK EMOBN ESX EX3 EXGXG F5P FEDTE FQGFK FSGXE FYUFA GNUQQ HCIFZ HMCUK HVGLF HZ~ IAO IH2 IHR INH INR ITC LGEZI LK8 LOTEE M0L M1P M2P M7P MM. N9A NADUK NAPCQ NNMJJ NXXTH O9- ODYON P2P PCBAR PQQKQ PROAC PSQYO Q2X QF4 QM4 QN7 QO4 RNR RNT RNTTT SHXYY SIXXV SNYQT SOJ SV3 TAOOD TBHMF TDRGL TSG TUS UKHRP WOW X7M AAYXX ABFSG ACMFV ACSTC AEZWR AFANA AFHIU AHWEU AIXLP ALPWD ATHPR CITATION NFIDA CGR CUY CVF ECM EIF NPM PHGZM PHGZT PJZUB PPXIY PQGLB 7QL 7U9 8FD C1K FR3 H94 K9. M7N P64 RC3 7X8 |
| ID | FETCH-LOGICAL-c375t-9a08e698903a779dda0edf9fab3525e8d55185599bad4eebfa030b784b1d40a33 |
| ISSN | 1740-1526 1740-1534 |
| IngestDate | Thu Jul 10 20:07:20 EDT 2025 Sat Aug 23 12:22:39 EDT 2025 Mon Jul 21 05:58:05 EDT 2025 Tue Jul 01 01:50:41 EDT 2025 Thu Apr 24 23:10:58 EDT 2025 Fri Feb 21 02:47:24 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Language | English |
| License | 2024. Springer Nature Limited. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c375t-9a08e698903a779dda0edf9fab3525e8d55185599bad4eebfa030b784b1d40a33 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 |
| ORCID | 0000-0001-6922-836X 0000-0003-3765-8853 |
| PMID | 39406893 |
| PQID | 3167799462 |
| PQPubID | 27584 |
| PageCount | 16 |
| ParticipantIDs | proquest_miscellaneous_3117072758 proquest_journals_3167799462 pubmed_primary_39406893 crossref_citationtrail_10_1038_s41579_024_01106_1 crossref_primary_10_1038_s41579_024_01106_1 springer_journals_10_1038_s41579_024_01106_1 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2025-03-01 |
| PublicationDateYYYYMMDD | 2025-03-01 |
| PublicationDate_xml | – month: 03 year: 2025 text: 2025-03-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | London |
| PublicationPlace_xml | – name: London – name: England |
| PublicationTitle | Nature reviews. Microbiology |
| PublicationTitleAbbrev | Nat Rev Microbiol |
| PublicationTitleAlternate | Nat Rev Microbiol |
| PublicationYear | 2025 |
| Publisher | Nature Publishing Group UK Nature Publishing Group |
| Publisher_xml | – name: Nature Publishing Group UK – name: Nature Publishing Group |
| References | L Mandell (1106_CR125) 2004; 72 E Blacher (1106_CR171) 2019; 572 M Jensen (1106_CR194) 2024; 9 S Akagawa (1106_CR14) 2022; 71 M Arumugam (1106_CR175) 2011; 473 H Song (1106_CR185) 2016; 31 A Alberts (1106_CR149) 2020; 11 JY Lee (1106_CR83) 2022; 22 P Ruas-Madiedo (1106_CR111) 2009; 75 MJ Pichler (1106_CR173) 2020; 11 L Wang (1106_CR153) 2020; 69 K Huang (1106_CR79) 2015; 415 Q Liu (1106_CR58) 2021; 11 E Hosseini (1106_CR74) 2011; 69 D Machado (1106_CR104) 2020; 61 S Kim (1106_CR142) 2020; 86 EK Costello (1106_CR30) 2010; 4 D Turck (1106_CR183) 2021; 19 RM McLoughlin (1106_CR145) 2003; 112 PX Wang (1106_CR12) 2020; 133 V Palmas (1106_CR41) 2022; 14 CS Kang (1106_CR154) 2013; 8 A Santacruz (1106_CR134) 2010; 104 S Ribo (1106_CR97) 2021; 13 AP Corfield (1106_CR76) 1992; 60 B Jia (1106_CR190) 2023; 31 M Wolter (1106_CR162) 2024; 20 MAG Hernández (1106_CR72) 2019; 11 S Fanning (1106_CR112) 2012; 109 B Trastoy (1106_CR101) 2020; 11 S Yang (1106_CR179) 2018; 90 SL King (1106_CR180) 2017; 1 R Xiang (1106_CR64) 2021; 547 MC Rodríguez-Daza (1106_CR117) 2021; 8 FF Anhê (1106_CR113) 2015; 64 I Kostopoulos (1106_CR67) 2021; 12 Z Ou (1106_CR201) 2020; 10 MF Maciel-Fiuza (1106_CR16) 2023; 14 P Garcia-Vello (1106_CR68) 2022; 32 1106_CR205 S Lukovac (1106_CR144) 2014; 5 J Reunanen (1106_CR65) 2015; 81 P Kuffa (1106_CR160) 2023; 31 F Bäckhed (1106_CR91) 2015; 17 AJ DeSana (1106_CR203) 2024; 14 Q-B Lv (1106_CR48) 2022; 12 M Derrien (1106_CR176) 2017; 106 N Karcher (1106_CR35) 2021; 22 ER Davenport (1106_CR147) 2015; 10 K Kosciow (1106_CR84) 2020; 149 F Lu (1106_CR121) 2021; 149 C Belzer (1106_CR20) 2017; 8 Z Bagheri (1106_CR13) 2022; 2022 SC Bridgeman (1106_CR73) 2020; 160 LE Tailford (1106_CR77) 2015; 6 M Derrien (1106_CR17) 2004; 54 R Zhai (1106_CR60) 2019; 9 JP Ouwerkerk (1106_CR136) 2013; 27 HS Yoon (1106_CR129) 2021; 6 A Peña-Cearra (1106_CR105) 2024; 7 Y Haneishi (1106_CR10) 2023; 24 A Christovich (1106_CR11) 2022; 13 RE Ley (1106_CR26) 2008; 320 F Wu (1106_CR141) 2020; 61 MC Rodríguez-Daza (1106_CR118) 2022; 24 C Depommier (1106_CR143) 2019; 25 A Everard (1106_CR188) 2011; 60 M Matijašić (1106_CR1) 2020; 21 SM Jandhyala (1106_CR9) 2015; 21 M Bae (1106_CR126) 2022; 608 JY Kim (1106_CR200) 2024; 47 P Konstanti (1106_CR164) 2024; 90 I Anso (1106_CR195) 2023; 14 N Daniel (1106_CR49) 2023; 72 B Shuoker (1106_CR80) 2023; 14 M Gurung (1106_CR95) 2024; 9 M Richter (1106_CR207) 2009; 106 M Derrien (1106_CR34) 2008; 74 S Ndongo (1106_CR57) 2022; 12 M Derrien (1106_CR19) 2010; 1 H Plovier (1106_CR122) 2016; 23 SG Sorboni (1106_CR15) 2022; 35 SY Geerlings (1106_CR54) 2021; 21 JF Pierre (1106_CR110) 2016; 311 C Belzer (1106_CR89) 2021; 30 H-H Chua (1106_CR196) 2024; 17 X Guo (1106_CR50) 2017; 18 S Zhao (1106_CR140) 2017; 58 R Kumar (1106_CR52) 2022; 11 N Ottman (1106_CR63) 2017; 12 EH Seck (1106_CR132) 2019; 43 T Hagi (1106_CR108) 2020; 104 NA Bokulich (1106_CR6) 2016; 8 X Gao (1106_CR123) 2024; 1871 LE Davey (1106_CR82) 2023; 8 A Everard (1106_CR22) 2013; 110 B Becken (1106_CR208) 2021; 12 ET Grant (1106_CR94) 2023; 15 X Guo (1106_CR37) 2016; 120 Y-F Liu (1106_CR197) 2024; 123 M Juárez-Fernández (1106_CR109) 2021; 10 S Xie (1106_CR128) 2024; 73 S Kim (1106_CR152) 2021; 13 RL Greer (1106_CR146) 2016; 7 1106_CR192 I Kostopoulos (1106_CR81) 2020; 10 MB Azad (1106_CR93) 2013; 185 RA Yunes (1106_CR165) 2016; 42 E Cario (1106_CR158) 2007; 132 C Ma (1106_CR181) 2020; 18 F Sommer (1106_CR27) 2016; 14 MC Collado (1106_CR36) 2007; 73 E Ansaldo (1106_CR150) 2019; 364 TS Rasmussen (1106_CR177) 2023; 15 JK Goodrich (1106_CR4) 2014; 159 E Biagi (1106_CR43) 2016; 26 A Pellegrino (1106_CR193) 2023; 15 DT Truong (1106_CR53) 2017; 27 X Fang (1106_CR169) 2021; 41 Y Ding (1106_CR202) 2021; 105 F Wang (1106_CR46) 2015; 25 DJ Shon (1106_CR99) 2022; 298 E-J Kang (1106_CR156) 2024; 15 J Elzinga (1106_CR66) 2024; 15 L Wu (1106_CR44) 2022; 8 AF Cătoi (1106_CR47) 2020; 1866 S Nayfach (1106_CR40) 2019; 568 L Li (1106_CR189) 2024; 15 DK Podolsky (1106_CR157) 2009; 137 JT Viera (1106_CR148) 2016; 11 KCH van der Ark (1106_CR69) 2018; 11 CB Van Buiten (1106_CR119) 2024; 13 LI Crouch (1106_CR85) 2020; 11 MC Dao (1106_CR133) 2016; 65 W Yang (1106_CR178) 2018; 14 R Sender (1106_CR2) 2016; 14 N Ottman (1106_CR21) 2017; 31 D Parada Venegas (1106_CR71) 2019; 10 XMC Dao (1106_CR135) 2019; 317 C-M Qiao (1106_CR198) 2024; 14 SY Geerlings (1106_CR38) 2018; 6 PA Dawson (1106_CR106) 2015; 56 C Belzer (1106_CR32) 2012; 6 S Reider (1106_CR116) 2022; 12 R Gilroy (1106_CR206) 2021; 9 J Yang (1106_CR184) 2016; 11 F De Vadder (1106_CR75) 2014; 156 MS Desai (1106_CR159) 2016; 167 B Van Der Lugt (1106_CR24) 2019; 16 Y Momozawa (1106_CR39) 2011; 6 K Kosciow (1106_CR86) 2019; 8 A Adak (1106_CR8) 2019; 76 A Hasani (1106_CR191) 2021; 70 NR Shin (1106_CR139) 2014; 63 A Parrish (1106_CR161) 2023; 8 C Gómez-Gallego (1106_CR186) 2012; 23 ER Davenport (1106_CR3) 2017; 15 K Lange (1106_CR5) 2016; 34 V Lombard (1106_CR182) 2014; 42 BK Perler (1106_CR7) 2023; 85 CA Olson (1106_CR166) 2018; 173 LM Cox (1106_CR170) 2021; 89 J Aakko (1106_CR90) 2017; 8 M-C Rodríguez-Daza (1106_CR120) 2020; 10 C Chelakkot (1106_CR23) 2018; 50 DE Roopchand (1106_CR114) 2015; 64 M Schneeberger (1106_CR137) 2015; 5 W Wu (1106_CR151) 2017; 8 Q Zhang (1106_CR131) 2023; 8 N Ottman (1106_CR61) 2016; 7 S-M Kim (1106_CR130) 2023; 31 KE Andersson (1106_CR187) 2013; 52 MD Berkhout (1106_CR87) 2022; 32 E Biagi (1106_CR42) 2010; 5 MWJ van Passel (1106_CR18) 2011; 6 SA Shetty (1106_CR174) 2022; 16 Y Shono (1106_CR163) 2016; 8 PD Cani (1106_CR25) 2022; 19 BJ Medley (1106_CR102) 2022; 298 KCH van der Ark (1106_CR107) 2017; 102 Z Li (1106_CR167) 2022; 27 TJ Green (1106_CR33) 2013; 166 N Kirmiz (1106_CR59) 2020; 86 X Meng (1106_CR98) 2021; 21 K Sonoyama (1106_CR29) 2009; 75 S Akira (1106_CR127) 2004; 4 H Guo (1106_CR199) 2024; 61 HV Carey (1106_CR28) 2013; 304 W Xi (1106_CR168) 2021; 62 TJ Hammer (1106_CR204) 2024; 32 MG Espey (1106_CR103) 2013; 55 LW Chia (1106_CR172) 2018; 111 N Ottman (1106_CR70) 2017; 83 B-S Kim (1106_CR45) 2019; 29 1106_CR78 MB Salem (1106_CR115) 2024; 10 DJ Shon (1106_CR100) 2020; 117 R Kikkert (1106_CR124) 2007; 22 JP Ouwerkerk (1106_CR31) 2016; 82 K Ligthart (1106_CR62) 2020; 28 J Zhang (1106_CR138) 2021; 8 D González (1106_CR51) 2023; 14 JP Ouwerkerk (1106_CR56) 2016; 66 L Padilla (1106_CR96) 2024; 206 JP Ouwerkerk (1106_CR88) 2022; 10 E Luna (1106_CR55) 2022; 88 A Bergström (1106_CR92) 2014; 80 H Earley (1106_CR155) 2019; 9 |
| References_xml | – volume: 15 year: 2023 ident: 1106_CR94 publication-title: EMBO Mol. Med. doi: 10.15252/emmm.202217241 – volume: 9 start-page: 1176 year: 2024 ident: 1106_CR194 publication-title: Nat. Microbiol. doi: 10.1038/s41564-024-01663-4 – volume: 88 year: 2022 ident: 1106_CR55 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.01487-21 – volume: 8 start-page: 2100536 year: 2021 ident: 1106_CR138 publication-title: Adv. Sci. doi: 10.1002/advs.202100536 – volume: 23 start-page: 107 year: 2016 ident: 1106_CR122 publication-title: Nat. Med. doi: 10.1038/nm.4236 – volume: 9 start-page: 239 year: 2019 ident: 1106_CR60 publication-title: Front. Cell Infect. Microbiol. doi: 10.3389/fcimb.2019.00239 – volume: 10 start-page: 1605 year: 2022 ident: 1106_CR88 publication-title: Microorganisms doi: 10.3390/microorganisms10081605 – volume: 304 start-page: R33 year: 2013 ident: 1106_CR28 publication-title: Am. J. Physiol. Regul. Integr. Comp. Physiol. doi: 10.1152/ajpregu.00387.2012 – volume: 18 start-page: 1884 year: 2020 ident: 1106_CR181 publication-title: J. Thromb. Haemost. doi: 10.1111/jth.14861 – volume: 25 start-page: 1096 year: 2019 ident: 1106_CR143 publication-title: Nat. Med. doi: 10.1038/s41591-019-0495-2 – volume: 60 start-page: 2775 year: 2011 ident: 1106_CR188 publication-title: Diabetes doi: 10.2337/db11-0227 – volume: 86 start-page: e03004 year: 2020 ident: 1106_CR142 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.03004-19 – volume: 85 start-page: 449 year: 2023 ident: 1106_CR7 publication-title: Annu. Rev. Physiol. doi: 10.1146/annurev-physiol-031522-092054 – volume: 72 start-page: 6446 year: 2004 ident: 1106_CR125 publication-title: Infect. Immun. doi: 10.1128/IAI.72.11.6446-6454.2004 – volume: 105 start-page: 8411 year: 2021 ident: 1106_CR202 publication-title: Appl. Microbiol. Biotechnol. doi: 10.1007/s00253-021-11622-2 – volume: 22 start-page: 2100125 year: 2022 ident: 1106_CR83 publication-title: Proteomics doi: 10.1002/pmic.202100125 – volume: 102 start-page: 372 year: 2017 ident: 1106_CR107 publication-title: Food Res. Int. doi: 10.1016/j.foodres.2017.09.004 – volume: 133 start-page: 808 year: 2020 ident: 1106_CR12 publication-title: Chin. Med. J. doi: 10.1097/CM9.0000000000000696 – volume: 6 start-page: 1449 year: 2012 ident: 1106_CR32 publication-title: ISME J. doi: 10.1038/ismej.2012.6 – volume: 75 start-page: 6451 year: 2009 ident: 1106_CR29 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.00692-09 – volume: 81 start-page: 3655 year: 2015 ident: 1106_CR65 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.04050-14 – volume: 16 start-page: 2144 year: 2022 ident: 1106_CR174 publication-title: ISME J. doi: 10.1038/s41396-022-01255-2 – volume: 608 start-page: 168 year: 2022 ident: 1106_CR126 publication-title: Nature doi: 10.1038/s41586-022-04985-7 – volume: 26 start-page: 1480 year: 2016 ident: 1106_CR43 publication-title: Curr. Biol. doi: 10.1016/j.cub.2016.04.016 – volume: 14 start-page: 2436 year: 2022 ident: 1106_CR41 publication-title: Nutrients doi: 10.3390/nu14122436 – volume: 31 start-page: 2007 year: 2023 ident: 1106_CR160 publication-title: Cell Host Microbe doi: 10.1016/j.chom.2023.10.016 – volume: 34 start-page: 260 year: 2016 ident: 1106_CR5 publication-title: Dig. Dis. doi: 10.1159/000443360 – volume: 31 start-page: 637 year: 2017 ident: 1106_CR21 publication-title: Best. Pract. Res. Clin. Gastroenterol. doi: 10.1016/j.bpg.2017.10.001 – ident: 1106_CR78 doi: 10.1101/2024.03.27.586211 – volume: 8 start-page: 563 year: 2017 ident: 1106_CR90 publication-title: Benef. Microbes doi: 10.3920/BM2016.0185 – volume: 14 year: 2024 ident: 1106_CR203 publication-title: Sci. Rep. doi: 10.1038/s41598-024-53430-4 – volume: 21 start-page: 298 year: 2021 ident: 1106_CR54 publication-title: BMC Microbiol. doi: 10.1186/s12866-021-02360-6 – volume: 109 start-page: 2108 year: 2012 ident: 1106_CR112 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1115621109 – volume: 62 start-page: 1246 year: 2021 ident: 1106_CR168 publication-title: J. Child. Psychol. Psychiatry doi: 10.1111/jcpp.13409 – volume: 106 start-page: 19126 year: 2009 ident: 1106_CR207 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0906412106 – volume: 8 start-page: 689456 year: 2021 ident: 1106_CR117 publication-title: Front. Nutr. doi: 10.3389/fnut.2021.689456 – volume: 18 year: 2017 ident: 1106_CR50 publication-title: BMC Genomics doi: 10.1186/s12864-017-4195-3 – volume: 15 year: 2024 ident: 1106_CR66 publication-title: Nat. Commun. doi: 10.1038/s41467-024-48770-8 – volume: 7 start-page: 1157 year: 2016 ident: 1106_CR61 publication-title: Front. Microbiol. doi: 10.3389/fmicb.2016.01157 – volume: 65 start-page: 426 year: 2016 ident: 1106_CR133 publication-title: Gut doi: 10.1136/gutjnl-2014-308778 – volume: 112 start-page: 598 year: 2003 ident: 1106_CR145 publication-title: J. Clin. Investig. doi: 10.1172/JCI17129 – volume: 41 start-page: 1172 year: 2021 ident: 1106_CR169 publication-title: Curr. Med. Sci. doi: 10.1007/s11596-021-2464-5 – volume: 149 start-page: 110648 year: 2021 ident: 1106_CR121 publication-title: Food Res. Int. doi: 10.1016/j.foodres.2021.110648 – volume: 83 start-page: e01014 year: 2017 ident: 1106_CR70 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.01014-17 – volume: 14 year: 2023 ident: 1106_CR80 publication-title: Nat. Commun. doi: 10.1038/s41467-023-37533-6 – volume: 568 start-page: 505 year: 2019 ident: 1106_CR40 publication-title: Nature doi: 10.1038/s41586-019-1058-x – volume: 21 start-page: 2668 year: 2020 ident: 1106_CR1 publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms21082668 – volume: 111 start-page: 859 year: 2018 ident: 1106_CR172 publication-title: Antonie Van. Leeuwenhoek doi: 10.1007/s10482-018-1040-x – volume: 15 start-page: 1815 year: 2023 ident: 1106_CR193 publication-title: Nutrients doi: 10.3390/nu15081815 – volume: 6 start-page: 75 year: 2018 ident: 1106_CR38 publication-title: Microorganisms doi: 10.3390/microorganisms6030075 – volume: 19 start-page: 625 year: 2022 ident: 1106_CR25 publication-title: Nat. Rev. Gastroenterol. Hepatol. doi: 10.1038/s41575-022-00631-9 – volume: 82 start-page: 6983 year: 2016 ident: 1106_CR31 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.01641-16 – volume: 8 start-page: 1863 year: 2023 ident: 1106_CR161 publication-title: Nat. Microbiol. doi: 10.1038/s41564-023-01464-1 – volume: 364 start-page: 1179 year: 2019 ident: 1106_CR150 publication-title: Science doi: 10.1126/science.aaw7479 – volume: 56 start-page: 1085 year: 2015 ident: 1106_CR106 publication-title: J. Lipid Res. doi: 10.1194/jlr.R054114 – volume: 473 start-page: 174 year: 2011 ident: 1106_CR175 publication-title: Nature doi: 10.1038/nature09944 – volume: 15 year: 2017 ident: 1106_CR3 publication-title: BMC Biol. doi: 10.1186/s12915-017-0454-7 – volume: 73 start-page: 7767 year: 2007 ident: 1106_CR36 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.01477-07 – volume: 24 start-page: 45 year: 2022 ident: 1106_CR118 publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms24010045 – volume: 89 start-page: 1195 year: 2021 ident: 1106_CR170 publication-title: Ann. Neurol. doi: 10.1002/ana.26084 – volume: 14 year: 2016 ident: 1106_CR2 publication-title: PLoS Biol. doi: 10.1371/journal.pbio.1002533 – volume: 1 start-page: 254 year: 2010 ident: 1106_CR19 publication-title: Gut Microbes doi: 10.4161/gmic.1.4.12778 – volume: 22 start-page: 1 year: 2021 ident: 1106_CR35 publication-title: Genome Biol. doi: 10.1186/s13059-021-02427-7 – volume: 8 start-page: 343ra82 year: 2016 ident: 1106_CR6 publication-title: Sci. Transl. Med. doi: 10.1126/scitranslmed.aad7121 – volume: 8 start-page: 1 year: 2017 ident: 1106_CR20 publication-title: mBio doi: 10.1128/mBio.00770-17 – volume: 5 start-page: e01438 year: 2014 ident: 1106_CR144 publication-title: mBio doi: 10.1128/mBio.01438-14 – volume: 76 start-page: 473 year: 2019 ident: 1106_CR8 publication-title: Cell. Mol. Life Sci. doi: 10.1007/s00018-018-2943-4 – volume: 110 start-page: 9066 year: 2013 ident: 1106_CR22 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1219451110 – volume: 12 start-page: 1 year: 2021 ident: 1106_CR67 publication-title: Front. Microbiol. doi: 10.3389/fmicb.2021.632454 – volume: 185 start-page: 385 year: 2013 ident: 1106_CR93 publication-title: CMAJ doi: 10.1503/cmaj.121189 – volume: 2022 start-page: 3845104 year: 2022 ident: 1106_CR13 publication-title: J. Oncol. doi: 10.1155/2022/3845104 – volume: 66 start-page: 4614 year: 2016 ident: 1106_CR56 publication-title: Int. J. Syst. Evol. Microbiol. doi: 10.1099/ijsem.0.001399 – volume: 11 year: 2016 ident: 1106_CR184 publication-title: PLoS ONE doi: 10.1371/journal.pone.0146144 – volume: 29 start-page: 429 year: 2019 ident: 1106_CR45 publication-title: J. Microbiol. Biotechnol. doi: 10.4014/jmb.1811.11023 – volume: 54 start-page: 1469 year: 2004 ident: 1106_CR17 publication-title: Int. J. Syst. Evol. Microbiol. doi: 10.1099/ijs.0.02873-0 – volume: 27 start-page: 25 year: 2013 ident: 1106_CR136 publication-title: Best. Pract. Res. Clin. Gastroenterol. doi: 10.1016/j.bpg.2013.03.001 – volume: 6 start-page: 81 year: 2015 ident: 1106_CR77 publication-title: Front. Genet. doi: 10.3389/fgene.2015.00081 – volume: 27 start-page: 626 year: 2017 ident: 1106_CR53 publication-title: Genome Res. doi: 10.1101/gr.216242.116 – volume: 106 start-page: 171 year: 2017 ident: 1106_CR176 publication-title: Microb. Pathog. doi: 10.1016/j.micpath.2016.02.005 – volume: 58 start-page: 1 year: 2017 ident: 1106_CR140 publication-title: J. Mol. Endocrinol. doi: 10.1530/JME-16-0054 – volume: 21 start-page: 8836 year: 2015 ident: 1106_CR9 publication-title: World J. Gastroenterol. doi: 10.3748/wjg.v21.i29.8787 – volume: 4 start-page: 499 year: 2004 ident: 1106_CR127 publication-title: Nat. Rev. Immunol. doi: 10.1038/nri1391 – volume: 14 year: 2023 ident: 1106_CR195 publication-title: Nat. Commun. doi: 10.1038/s41467-023-37324-z – volume: 7 start-page: 192 year: 2024 ident: 1106_CR105 publication-title: Commun. Biol. doi: 10.1038/s42003-024-05867-6 – volume: 42 start-page: 490 year: 2014 ident: 1106_CR182 publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkt1178 – volume: 16 start-page: 1 year: 2019 ident: 1106_CR24 publication-title: Immun. Ageing doi: 10.1186/s12979-019-0145-z – volume: 104 start-page: 10641 year: 2020 ident: 1106_CR108 publication-title: Appl. Microbiol. Biotechnol. doi: 10.1007/s00253-020-10976-3 – volume: 317 start-page: E446 year: 2019 ident: 1106_CR135 publication-title: Am. J. Physiol. Endocrinol. Metab. doi: 10.1152/ajpendo.00140.2019 – volume: 43 start-page: 862 year: 2019 ident: 1106_CR132 publication-title: Int. J. Obes. doi: 10.1038/s41366-018-0201-3 – volume: 12 start-page: 1 year: 2017 ident: 1106_CR63 publication-title: PLoS ONE doi: 10.1371/journal.pone.0173004 – volume: 5 year: 2015 ident: 1106_CR137 publication-title: Sci. Rep. doi: 10.1038/srep16643 – volume: 28 start-page: 340 year: 2020 ident: 1106_CR62 publication-title: Trends Microbiol. doi: 10.1016/j.tim.2020.02.003 – volume: 70 start-page: 001435 year: 2021 ident: 1106_CR191 publication-title: J. Med. Microbiol. doi: 10.1099/jmm.0.001435 – volume: 4 start-page: 1375 year: 2010 ident: 1106_CR30 publication-title: ISME J. doi: 10.1038/ismej.2010.71 – volume: 69 start-page: 245 year: 2011 ident: 1106_CR74 publication-title: Nutr. Rev. doi: 10.1111/j.1753-4887.2011.00388.x – volume: 86 start-page: e02117 year: 2020 ident: 1106_CR59 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.02117-19 – volume: 10 year: 2020 ident: 1106_CR120 publication-title: Sci. Rep. doi: 10.1038/s41598-020-58863-1 – volume: 120 start-page: 452 year: 2016 ident: 1106_CR37 publication-title: J. Appl. Microbiol. doi: 10.1111/jam.13022 – volume: 12 year: 2022 ident: 1106_CR57 publication-title: Sci. Rep. doi: 10.1038/s41598-022-25873-0 – volume: 13 start-page: 1892441 year: 2021 ident: 1106_CR152 publication-title: Gut Microbes doi: 10.1080/19490976.2021.1892441 – volume: 23 start-page: 1508 year: 2012 ident: 1106_CR186 publication-title: J. Nutr. Biochem. doi: 10.1016/j.jnutbio.2011.10.003 – volume: 123 start-page: 155249 year: 2024 ident: 1106_CR197 publication-title: Phytomedicine doi: 10.1016/j.phymed.2023.155249 – volume: 11 year: 2020 ident: 1106_CR173 publication-title: Nat. Commun. doi: 10.1038/s41467-020-17075-x – volume: 132 start-page: 1359 year: 2007 ident: 1106_CR158 publication-title: Gastroenterology doi: 10.1053/j.gastro.2007.02.056 – volume: 90 year: 2024 ident: 1106_CR164 publication-title: Appl. Env. Microbiol. doi: 10.1128/aem.01121-23 – volume: 298 start-page: 102439 year: 2022 ident: 1106_CR102 publication-title: J. Biol. Chem. doi: 10.1016/j.jbc.2022.102439 – volume: 35 year: 2022 ident: 1106_CR15 publication-title: Clin. Microbiol. Rev. doi: 10.1128/CMR.00338-20 – volume: 320 start-page: 1647 year: 2008 ident: 1106_CR26 publication-title: Science doi: 10.1126/science.1155725 – volume: 10 start-page: 12 year: 2020 ident: 1106_CR201 publication-title: Nutr. Diabetes doi: 10.1038/s41387-020-0115-8 – volume: 17 start-page: 690 year: 2015 ident: 1106_CR91 publication-title: Cell Host Microbe doi: 10.1016/j.chom.2015.04.004 – volume: 75 start-page: 1204 year: 2009 ident: 1106_CR111 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.00908-08 – volume: 8 start-page: 339ra71 year: 2016 ident: 1106_CR163 publication-title: Sci. Transl. Med. doi: 10.1126/scitranslmed.aaf2311 – volume: 11 start-page: 2084 year: 2022 ident: 1106_CR52 publication-title: Cells doi: 10.3390/cells11132084 – volume: 6 year: 2011 ident: 1106_CR39 publication-title: PLoS ONE doi: 10.1371/journal.pone.0016952 – volume: 19 year: 2021 ident: 1106_CR183 publication-title: EFSA J. – volume: 25 start-page: 1195 year: 2015 ident: 1106_CR46 publication-title: J. Microbiol. Biotechnol. doi: 10.4014/jmb.1410.10014 – volume: 8 year: 2013 ident: 1106_CR154 publication-title: PLoS ONE doi: 10.1371/journal.pone.0076520 – volume: 8 year: 2022 ident: 1106_CR44 publication-title: NPJ Biofilms Microbiomes doi: 10.1038/s41522-022-00366-0 – volume: 12 start-page: 00478 year: 2021 ident: 1106_CR208 publication-title: mBio doi: 10.1128/mBio.00478-21 – volume: 61 start-page: 821 year: 2024 ident: 1106_CR199 publication-title: Mol. Neurobiol. doi: 10.1007/s12035-023-03602-6 – volume: 17 start-page: 361 year: 2024 ident: 1106_CR196 publication-title: Cell Mol. Gastroenterol. Hepatol. doi: 10.1016/j.jcmgh.2023.12.003 – volume: 8 start-page: 1450 year: 2023 ident: 1106_CR82 publication-title: Nat. Microbiol. doi: 10.1038/s41564-023-01407-w – volume: 10 year: 2020 ident: 1106_CR81 publication-title: Sci. Rep. doi: 10.1038/s41598-020-71113-8 – volume: 547 start-page: 59 year: 2021 ident: 1106_CR64 publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2021.02.022 – volume: 15 start-page: 2208504 year: 2023 ident: 1106_CR177 publication-title: Gut Microbes doi: 10.1080/19490976.2023.2208504 – volume: 61 start-page: 102135 year: 2020 ident: 1106_CR104 publication-title: Anaerobe doi: 10.1016/j.anaerobe.2019.102135 – volume: 10 year: 2015 ident: 1106_CR147 publication-title: PLoS ONE doi: 10.1371/journal.pone.0140301 – volume: 27 start-page: 4123 year: 2022 ident: 1106_CR167 publication-title: Mol. Psychiatry doi: 10.1038/s41380-022-01569-9 – volume: 72 start-page: 906 year: 2023 ident: 1106_CR49 publication-title: Gut doi: 10.1136/gutjnl-2021-326835 – volume: 173 start-page: 1728 year: 2018 ident: 1106_CR166 publication-title: Cell doi: 10.1016/j.cell.2018.04.027 – volume: 15 start-page: 1354447 year: 2024 ident: 1106_CR189 publication-title: Front. Microbiol. doi: 10.3389/fmicb.2024.1354447 – volume: 311 start-page: G286 year: 2016 ident: 1106_CR110 publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00202.2016 – volume: 1866 start-page: 165765 year: 2020 ident: 1106_CR47 publication-title: Biochim. Biophys. Acta, Mol. Cell Res. doi: 10.1016/j.bbadis.2020.165765 – volume: 149 start-page: 331 year: 2020 ident: 1106_CR84 publication-title: Int. J. Biol. Macromol. doi: 10.1016/j.ijbiomac.2020.01.246 – volume: 7 start-page: 1 year: 2016 ident: 1106_CR146 publication-title: Nat. Commun. doi: 10.1038/ncomms13329 – volume: 11 start-page: 1943 year: 2019 ident: 1106_CR72 publication-title: Nutrients doi: 10.3390/nu11081943 – volume: 31 start-page: 1021 year: 2023 ident: 1106_CR130 publication-title: Cell Host Microbe doi: 10.1016/j.chom.2023.05.007 – volume: 64 start-page: 872 year: 2015 ident: 1106_CR113 publication-title: Gut doi: 10.1136/gutjnl-2014-307142 – volume: 61 start-page: 102138 year: 2020 ident: 1106_CR141 publication-title: Anaerobe doi: 10.1016/j.anaerobe.2019.102138 – volume: 1871 start-page: 119630 year: 2024 ident: 1106_CR123 publication-title: Biochim. Biophys. Acta, Mol. Cell Res. doi: 10.1016/j.bbamcr.2023.119630 – volume: 6 start-page: 563 year: 2021 ident: 1106_CR129 publication-title: Nat. Microbiol. doi: 10.1038/s41564-021-00880-5 – volume: 104 start-page: 83 year: 2010 ident: 1106_CR134 publication-title: Br. J. Nutr. doi: 10.1017/S0007114510000176 – volume: 15 year: 2024 ident: 1106_CR156 publication-title: Nat. Commun. doi: 10.1038/s41467-024-47275-8 – ident: 1106_CR192 doi: 10.1007/s12094-024-03493-6 – volume: 55 start-page: 130 year: 2013 ident: 1106_CR103 publication-title: Free. Radic. Biol. Med. doi: 10.1016/j.freeradbiomed.2012.10.554 – volume: 14 year: 2018 ident: 1106_CR178 publication-title: Mol. Syst. Biol. doi: 10.15252/msb.20188486 – volume: 60 start-page: 3971 year: 1992 ident: 1106_CR76 publication-title: Infect. Immun. doi: 10.1128/iai.60.10.3971-3978.1992 – volume: 20 start-page: 596 year: 2024 ident: 1106_CR162 publication-title: Mol. Syst. Biol. doi: 10.1038/s44320-024-00036-7 – volume: 159 start-page: 789 year: 2014 ident: 1106_CR4 publication-title: Cell doi: 10.1016/j.cell.2014.09.053 – volume: 11 year: 2020 ident: 1106_CR101 publication-title: Nat. Commun. doi: 10.1038/s41467-020-18696-y – volume: 10 start-page: 277 year: 2019 ident: 1106_CR71 publication-title: Front. Immunol. doi: 10.3389/fimmu.2019.00277 – volume: 298 start-page: 101917 year: 2022 ident: 1106_CR99 publication-title: J. Biol. Chem. doi: 10.1016/j.jbc.2022.101917 – volume: 69 start-page: 1988 year: 2020 ident: 1106_CR153 publication-title: Gut doi: 10.1136/gutjnl-2019-320105 – volume: 137 start-page: 209 year: 2009 ident: 1106_CR157 publication-title: Gastroenterology doi: 10.1053/j.gastro.2009.03.007 – volume: 166 start-page: 286 year: 2013 ident: 1106_CR33 publication-title: Vet. Microbiol. doi: 10.1016/j.vetmic.2013.05.009 – volume: 24 start-page: 3817 year: 2023 ident: 1106_CR10 publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms24043817 – volume: 32 start-page: 132 year: 2024 ident: 1106_CR204 publication-title: Trends Microbiol. doi: 10.1016/j.tim.2023.07.012 – volume: 9 year: 2021 ident: 1106_CR206 publication-title: PeerJ doi: 10.7717/peerj.10941 – volume: 21 start-page: 72 year: 2021 ident: 1106_CR98 publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms21010072 – ident: 1106_CR205 doi: 10.1099/ijsem.0.005697 – volume: 156 start-page: 84 year: 2014 ident: 1106_CR75 publication-title: Cell doi: 10.1016/j.cell.2013.12.016 – volume: 8 start-page: 1804 year: 2017 ident: 1106_CR151 publication-title: Front. Microbiol. doi: 10.3389/fmicb.2017.01804 – volume: 52 start-page: 1755 year: 2013 ident: 1106_CR187 publication-title: Eur. J. Nutr. doi: 10.1007/s00394-012-0479-1 – volume: 74 start-page: 1646 year: 2008 ident: 1106_CR34 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.01226-07 – volume: 572 start-page: 474 year: 2019 ident: 1106_CR171 publication-title: Nature doi: 10.1038/s41586-019-1443-5 – volume: 11 start-page: 476 year: 2018 ident: 1106_CR69 publication-title: Microb. Biotechnol. doi: 10.1111/1751-7915.13033 – volume: 12 start-page: 957439 year: 2022 ident: 1106_CR48 publication-title: Front. Cell Infect. Microbiol. doi: 10.3389/fcimb.2022.957439 – volume: 11 start-page: 698914 year: 2021 ident: 1106_CR58 publication-title: Front. Cell Infect. Microbiol. doi: 10.3389/fcimb.2021.698914 – volume: 8 start-page: 424 year: 2023 ident: 1106_CR131 publication-title: Nat. Microbiol. doi: 10.1038/s41564-023-01366-2 – volume: 32 start-page: 712 year: 2022 ident: 1106_CR68 publication-title: Glycobiology doi: 10.1093/glycob/cwac027 – volume: 10 year: 2024 ident: 1106_CR115 publication-title: Heliyon doi: 10.1016/j.heliyon.2024.e27527 – volume: 22 start-page: 145 year: 2007 ident: 1106_CR124 publication-title: Oral. Microbiol. Immunol. doi: 10.1111/j.1399-302X.2007.00335.x – volume: 9 year: 2019 ident: 1106_CR155 publication-title: Sci. Rep. doi: 10.1038/s41598-019-51878-3 – volume: 31 start-page: 76 year: 2023 ident: 1106_CR190 publication-title: Trends Microbiol. doi: 10.1016/j.tim.2022.08.003 – volume: 64 start-page: 2847 year: 2015 ident: 1106_CR114 publication-title: Diabetes doi: 10.2337/db14-1916 – volume: 11 year: 2016 ident: 1106_CR148 publication-title: PLoS ONE doi: 10.1371/journal.pone.0157607 – volume: 14 start-page: 1098386 year: 2023 ident: 1106_CR16 publication-title: Front. Microbiol. doi: 10.3389/fmicb.2023.1098386 – volume: 10 start-page: 2001 year: 2021 ident: 1106_CR109 publication-title: Antioxidants doi: 10.3390/antiox10122001 – volume: 415 start-page: 60 year: 2015 ident: 1106_CR79 publication-title: Carbohydr. Res. doi: 10.1016/j.carres.2015.08.001 – volume: 160 start-page: 105174 year: 2020 ident: 1106_CR73 publication-title: Pharmacol. Res. doi: 10.1016/j.phrs.2020.105174 – volume: 11 start-page: 596103 year: 2020 ident: 1106_CR149 publication-title: Front. Immunol. doi: 10.3389/fimmu.2020.596103 – volume: 80 start-page: 2889 year: 2014 ident: 1106_CR92 publication-title: Appl. Env. Microbiol. doi: 10.1128/AEM.00342-14 – volume: 32 start-page: 182 year: 2022 ident: 1106_CR87 publication-title: Glycobiology doi: 10.1093/glycob/cwab105 – volume: 30 start-page: 13 year: 2021 ident: 1106_CR89 publication-title: Trends Microbiol. doi: 10.1016/j.tim.2021.06.003 – volume: 206 year: 2024 ident: 1106_CR96 publication-title: J. Bacteriol. doi: 10.1128/jb.00334-23 – volume: 5 year: 2010 ident: 1106_CR42 publication-title: PLoS ONE doi: 10.1371/journal.pone.0010667 – volume: 14 start-page: 1655 year: 2016 ident: 1106_CR27 publication-title: Cell Rep. doi: 10.1016/j.celrep.2016.01.026 – volume: 47 start-page: 1642 year: 2024 ident: 1106_CR200 publication-title: Hypertens. Res. doi: 10.1038/s41440-024-01627-5 – volume: 13 start-page: 304 year: 2024 ident: 1106_CR119 publication-title: Antioxidants doi: 10.3390/antiox13030304 – volume: 42 start-page: 197 year: 2016 ident: 1106_CR165 publication-title: Anaerobe doi: 10.1016/j.anaerobe.2016.10.011 – volume: 13 start-page: eabb0322 year: 2021 ident: 1106_CR97 publication-title: Sci. Transl. Med. doi: 10.1126/scitranslmed.abb0322 – volume: 8 start-page: 1 year: 2019 ident: 1106_CR86 publication-title: Microbiologyopen doi: 10.1002/mbo3.796 – volume: 73 start-page: 78 year: 2024 ident: 1106_CR128 publication-title: Gut doi: 10.1136/gutjnl-2023-329996 – volume: 63 start-page: 727 year: 2014 ident: 1106_CR139 publication-title: Gut doi: 10.1136/gutjnl-2012-303839 – volume: 13 start-page: 946248 year: 2022 ident: 1106_CR11 publication-title: Front. Immunol. doi: 10.3389/fimmu.2022.946248 – volume: 6 year: 2011 ident: 1106_CR18 publication-title: PLoS ONE doi: 10.1371/journal.pone.0016876 – volume: 12 start-page: 1479 year: 2022 ident: 1106_CR116 publication-title: J. Pers. Med. doi: 10.3390/jpm12091479 – volume: 50 year: 2018 ident: 1106_CR23 publication-title: Exp. Mol. Med. doi: 10.1038/emm.2017.282 – volume: 14 start-page: 1238580 year: 2023 ident: 1106_CR51 publication-title: Front. Microbiol. doi: 10.3389/fmicb.2023.1238580 – volume: 11 year: 2020 ident: 1106_CR85 publication-title: Nat. Commun. doi: 10.1038/s41467-020-17847-5 – volume: 9 year: 2024 ident: 1106_CR95 publication-title: mSystems doi: 10.1128/msystems.00294-24 – volume: 117 start-page: 21299 year: 2020 ident: 1106_CR100 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.2012196117 – volume: 31 start-page: 1462 year: 2016 ident: 1106_CR185 publication-title: J. Gastroenterol. Hepatol. doi: 10.1111/jgh.13278 – volume: 167 start-page: 1339 year: 2016 ident: 1106_CR159 publication-title: Cell doi: 10.1016/j.cell.2016.10.043 – volume: 90 start-page: 8261 year: 2018 ident: 1106_CR179 publication-title: Anal. Chem. doi: 10.1021/acs.analchem.8b01834 – volume: 14 start-page: 238 year: 2024 ident: 1106_CR198 publication-title: Brain Sci. doi: 10.3390/brainsci14030238 – volume: 71 start-page: 301 year: 2022 ident: 1106_CR14 publication-title: Allergol. Int. doi: 10.1016/j.alit.2022.02.004 – volume: 1 start-page: 429 year: 2017 ident: 1106_CR180 publication-title: Blood Adv. doi: 10.1182/bloodadvances.2016002121 |
| SSID | ssj0025572 |
| Score | 2.5900323 |
| SecondaryResourceType | review_article |
| Snippet | Akkermansia muciniphila
is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic... Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic... |
| SourceID | proquest pubmed crossref springer |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 162 |
| SubjectTerms | 631/326/2565/2134 631/326/41/1969 692/4020/2741/2135 Akkermansia - classification Akkermansia - genetics Akkermansia - physiology Akkermansia muciniphila Animals Bacteria Biomarkers Biomedical and Life Sciences Ecological effects Ecology Ecophysiology Gastrointestinal Microbiome - physiology Host Microbial Interactions Human performance Humans Infectious Diseases Intestinal microflora Intestinal Mucosa - microbiology Life Sciences Medical Microbiology Microbiology Microbiomes Microbiota Microorganisms Mucins - metabolism Parasitology Phylogeny Probiotics Probiotics - therapeutic use Review Article Therapeutic applications Verrucomicrobia - classification Verrucomicrobia - genetics Verrucomicrobia - physiology Virology |
| Title | Akkermansia muciniphila: biology, microbial ecology, host interactions and therapeutic potential |
| URI | https://link.springer.com/article/10.1038/s41579-024-01106-1 https://www.ncbi.nlm.nih.gov/pubmed/39406893 https://www.proquest.com/docview/3167799462 https://www.proquest.com/docview/3117072758 |
| Volume | 23 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Pb5swFLa2VpN2mbqfZe0mT9otoYNgA94tnZpVU5ddEik7MQNGRUkhCnBo__o9G2MysU3dLihyACO_D_Oe_b7vIfSe-tzNAp7YsXCJTThNbMZSYnMS0tRxw5QrVtrXuX-5JF9WdNVXRVXskjo-S-5-yyv5H6tCG9hVsmT_wbLmptAAv8G-cAQLw_FeNp6u13JiLaqcj26aJC_y7XW-UdV24p6GcpMrsSWwhUhMoyR3KK2IXctsqLpUyo6NNdqWtcwk0s-g_de50gHVhJfqTGbdGyEng7KSF0XZqFlHLsxLnqaJ-sVufV02HU3othJ9yvFnoaS32rV6KSQNwPzeX7i505xFiMX5_mLFhPbZWnp-DeRWMtXrl2LYNpjRW_32CvyMgNngUNjSYfFtt_9-dXv282_RbHl1FS0uVouH6HACcQNMfIfT2fn53MTglKp6XqZPzaOCXj4M-_jVVxkEIIPNc-WTLI7QEx1M4GmLjKfogSieoUdtedHb5-jHHj7wHj4-Ym2xMTbYwBobYyyRgfeRgQEZeA8Z2CDjBVrOLhafLm1dUcNOvIDWNuNOKGTJUMfjQcDSlDsizVjGY6mKK8JU6vNJDbqYp0SIOOPwDYiDkMRuShzueS_RQVEW4hhhj4Y8oa7ISEoIy7LYZZz7gnqU-AkMrIXcbuyiRMvNy6onm0ilPXhh1I53BOMdqfGOXAuNzDXbVmzlr2efdiaJ9EtZRVLYIWCM-BMLvTN_w5Qp98F4IcpGnuMGDvjtNLTQq9aUpjuPgYcLPryFxp1t-5v_-Vle36OzE_S4fyVO0UG9a8Qb8Gjr-K1G6U9eJ5_f |
| linkProvider | Library Specific Holdings |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Akkermansia+muciniphila%3A+biology%2C+microbial+ecology%2C+host+interactions+and+therapeutic+potential&rft.jtitle=Nature+reviews.+Microbiology&rft.au=Ioannou%2C+Athanasia&rft.au=Berkhout%2C+Maryse+D&rft.au=Geerlings%2C+Sharon+Y&rft.au=Belzer%2C+Clara&rft.date=2025-03-01&rft.issn=1740-1534&rft.eissn=1740-1534&rft_id=info:doi/10.1038%2Fs41579-024-01106-1&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1740-1526&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1740-1526&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1740-1526&client=summon |