Association of biomarkers of inflammation and HLA-DRB1 gene locus with risk of developing rheumatoid arthritis in females

• Published in: Rheumatology international Vol. 39; no. 12; pp. 2147 - 2157
• Main Authors: Klimenta, Biljana, Nefic, Hilada, Prodanovic, Nenad, Jadric, Radivoj, Hukic, Fatima
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2019; Springer Nature B.V
• Subjects: Biomarkers; C-reactive protein; Gene loci; Genes and Disease; Medicine; Medicine & Public Health; Rheumatoid arthritis; Rheumatology; Rheumatoid arthritis (RA); C-reactive protein (CRP); Erythrocyte sedimentation rate (ESR); gene; -; HLA-DRB1 gene

Rheumatoid arthritis (RA) is an autoimmune disease causing chronic inflammation of the joints. Multiple factors, including HLA - DRB1 gene variants, influence the susceptibility to RA. The HLA - DRB1 gene is part of a family of genes called the human leukocyte antigen (HLA) complex. In this study, w...