Relationship between visceral adipose tissue and genetic mutations (VHL and KDM5C) in clear cell renal cell carcinoma

• Published in: Radiologia medica Vol. 126; no. 5; pp. 645 - 651
• Main Authors: Greco, Federico, Mallio, Carlo Augusto
• Format: Journal Article
• Language: English
• Published: Milan Springer Milan 01.05.2021; Springer Nature B.V
• Subjects: Abdominal Radiology; Adipose tissue; Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell - diagnostic imaging; Carcinoma, Renal Cell - genetics; Diagnostic Radiology; Histone Demethylases - genetics; Humans; Imaging; Interventional Radiology; Intra-Abdominal Fat; Kidney cancer; Kidney Neoplasms - diagnostic imaging; Kidney Neoplasms - genetics; Male; Medicine; Medicine & Public Health; Middle Aged; Mutation; Neuroradiology; Radiology; Retrospective Studies; Tomography, X-Ray Computed; Ultrasound; Von Hippel-Lindau Tumor Suppressor Protein - genetics; Adipocyte; CT; KDM5C; Clear cell renal cell carcinoma; Visceral adipose tissue; VHL

Background The sequencing of the renal cell carcinoma (RCC) genome has detected several mutations with prognostic meaning. The association between visceral adipose tissue (VAT) and clear cell renal cell carcinoma (ccRCC) is well known. The relationship among abdominal adipose tissue distribution and...