Clinical relevance of glycosylation in triple negative breast cancer: a review

• Published in: Glycoconjugate journal Vol. 41; no. 2; pp. 79 - 91
• Main Authors: Chakraborty, Mrinmoy, Kaur, Jasmine, Gunjan, Kathpalia, Meghavi, Kaur, Navkiran
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2024; Springer Nature B.V
• Subjects: Biochemistry; Biomarkers, Tumor - metabolism; Biomedical and Life Sciences; Breast cancer; Cell adhesion; Clinical Relevance; Diagnosis; Female; Glycosylation; Humans; Immune checkpoint inhibitors; Immune response; Life Sciences; Mannose; Pathology; PD-L1 protein; Review; Therapeutic targets; Triple Negative Breast Neoplasms - metabolism; Tumors; Glycosylation; N-linked glycosylation; Signalling pathways in triple negative breast cancer; Triple negative breast cancer; O-linked glycosylation

Glycosylation alterations in TNBC have significant implications for tumor behavior, diagnosis, prognosis, and therapeutic strategies. Dysregulated glycosylation affects cell adhesion, signaling, immune recognition, and response to therapy in TNBC. Different types of glycosylation, including N-linked...