Trichloroacetic acid model to accurately capture the efficacy of treatments for postinflammatory hyperpigmentation

• Published in: Archives of Dermatological Research Vol. 312; no. 10; pp. 725 - 730
• Main Authors: Lyons, Alexis B., Kohli, Indermeet, Nahhas, Amanda F., Braunberger, Taylor L., Mohammad, Tasneem F., Nicholson, Cynthia L., Nartker, Nathan T., Modi, Krishna, Matsui, Mary S., Lim, Henry W., Hamzavi, Iltefat H.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2020; Springer Nature B.V
• Subjects: Acne; Antioxidants; Clinical trials; Dermatology; Hyperpigmentation; Immunoglobulin A; Inflammation; Medicine; Medicine & Public Health; Original Paper; Patients; Pigments; Skin; Statistical analysis; Topical medication; Trichloroacetic acid; Trichloroacetic acid; Model; Hypermelanosis; Bakuchiol; Acne; Postinflammatory hyperpigmentation

Postinflammatory hyperpigmentation (PIH) occurs following cutaneous injury and is common following resolution of acne especially in patients with skin of color. The objective of this study was to further validate a trichloroacetic acid (TCA)-induced PIH model and compare it to acne-induced PIH using...