Circulating metabolites of Borneolum syntheticum (Bingpian) ameliorate atherosclerosis in ApoE−/− mice via inhibiting macrophage foam-cell formation - He, Rong-rong; Ma, Chuan-rui; He, Xin; Dong, Yan-xi; Li, Hui; Chu, Zi-xuan; Yang, Xi-he; Wang, Jia-qi; Wang, Ting; Wang, Feng-qing; Du, Fei-fei; Rao, Ying; et al. (Acta pharmacologica Sinica, 2025)
Keywords: Animals; Apolipoprotein E; Apolipoproteins E - metabolism; Arteriosclerosis; Atherosclerosis; Atherosclerosis - drug therapy; Atherosclerosis - metabolism; Bioavailability; Biomedical and Life Sciences; Biomedicine; Borneol; Camphanes - pharmacology; Camphor; Cardiovascular disease; Coronary artery disease; Diet, High-Fat; Drugs, Chinese Herbal - pharmacology; Drugs, Chinese Herbal - therapeutic use; Female; Foam Cells - drug effects; Foam Cells - metabolism; Heart diseases; Herbal medicine; High fat diet; Human subjects; Humans; Immunology; Internal Medicine; Lipoproteins, LDL - metabolism; Macrophages; Male; Medical Microbiology; Membrane permeability; Metabolism; Metabolites; Mice; Mice, Inbred C57BL; Pharmacodynamics; Pharmacology/Toxicology; Vaccine; atherosclerosis; isoborneol; metabolism; Bingpian; borneol; Borneolum syntheticum