Margin status impacts survival after pancreaticoduodenectomy but negative margins should not be pursued

• Published in: The American surgeon Vol. 80; no. 4; pp. 353 - 360
• Main Authors: Mathur, Abhishek, Ross, Sharona B, Luberice, Kenneth, Kurian, Tony, Vice, Michelle, Toomey, Paul, Rosemurgy, Alexander S
• Format: Journal Article
• Language: English
• Published: United States SAGE PUBLICATIONS, INC 01.04.2014
• Subjects: Adenocarcinoma - pathology; Adenocarcinoma - surgery; Aged; Carcinoma, Pancreatic Ductal - pathology; Carcinoma, Pancreatic Ductal - surgery; Chemotherapy; Female; Frozen Sections; Humans; Male; Multivariate analysis; Neoplasm Grading; Neoplasm Staging; Pancreas; Pancreatic cancer; Pancreatic Neoplasms - pathology; Pancreatic Neoplasms - surgery; Pancreaticoduodenectomy; Pathology; Reoperation; Survival Rate; Tomography; Treatment Outcome; Tumors; Veins & arteries

Negative margins are the goal with pancreaticoduodenectomy for pancreatic adenocarcinoma. Thereby, margins are assessed intraoperatively with frozen section analysis and negative margins are pursued. This study was undertaken to determine the impact of margin status with pancreaticoduodenectomy for...