Three new lanostane triterpenoids and two new amides from Alternaria sp. with NLRP3 inflammasome inhibitory activity - Bi, De-Wen; Feng, Jian; Pang, Wen-Hui; Yang, Peng-Yun; Xu, Yao-Jun; Aurang Zeb, Muhammad; Wang, Meng-Ru; Zhang, Xing-Jie; Li, Xiao-Li; Zhang, Rui-Han; Wang, Wei-Guang; Xiao, Wei-Lie (Natural product research, 2024)
Keywords: Acetic acid; Alternaria; Alternaria - chemistry; Alternaria sp. gx-2; Amides; Amides - chemistry; Amides - isolation & purification; Amides - pharmacology; Animals; anti-inflammatory activity; Anti-inflammatory agents; Anti-Inflammatory Agents - chemistry; Anti-Inflammatory Agents - pharmacology; Endophytes; Ethyl acetate; fungi; Humans; Inflammasomes; Inflammasomes - antagonists & inhibitors; Inflammation; L-Lactate dehydrogenase; Lactate dehydrogenase; Lanosterol - analogs & derivatives; Lanosterol - chemistry; Lanosterol - pharmacology; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Monophenol Monooxygenase - antagonists & inhibitors; NLR Family, Pyrin Domain-Containing 3 Protein - antagonists & inhibitors; NLRP3 inflammasome; NMR; Nuclear magnetic resonance; spectral analysis; Triterpenes - chemistry; Triterpenes - isolation & purification; Triterpenes - pharmacology; Triterpenoids; Tyrosinase; amides; NLRP3 inflammasome; tyrosinase; Alternaria sp. gx-2; triterpenoids