Regulatory T cells in the face of the intestinal microbiota

• Published in: Nature reviews. Immunology Vol. 23; no. 11; pp. 749 - 762
• Main Authors: Ramanan, Deepshika, Pratama, Alvin, Zhu, Yangyang, Venezia, Olivia, Sassone-Corsi, Martina, Chowdhary, Kaitavjeet, Galván-Peña, Silvia, Sefik, Esen, Brown, Chrysothemis, Gélineau, Adélaïde, Mathis, Diane, Benoist, Christophe
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.11.2023; Nature Publishing Group
• Subjects: 631/250/1619/554; 631/250/347; 692/4020/2741/2135; Antigens; Biomedical and Life Sciences; Biomedicine; Food; Forkhead Transcription Factors; Foxp3 protein; Gastrointestinal Microbiome; Homeostasis; Humans; Immunology; Immunoregulation; Influence; Intestinal microflora; Intestine; Intestines; Lymphatic system; Lymphocytes; Lymphocytes T; Microbiota; Microorganisms; Oncology; Pathogenesis; Pathogens; Receptors, Antigen, T-Cell; Review Article; Small intestine; T cell receptors; T-Lymphocytes, Regulatory; Thymus gland; Transcription factors; Weaning

Regulatory T cells (T reg cells) are key players in ensuring a peaceful coexistence with microorganisms and food antigens at intestinal borders. Startling new information has appeared in recent years on their diversity, the importance of the transcription factor FOXP3, how T cell receptors influence...