A galacturonan from Dioscorea opposita Thunb. regulates fecal and impairs IL-1 and IL-6 expression in diarrhea mice

• Published in: Glycoconjugate journal Vol. 39; no. 1; pp. 131 - 141
• Main Authors: Pan, Hao-Yu, Zhang, Chun-Qian, Zhang, Xiu-Qi, Zeng, Hui, Dong, Chun-hong, Chen, Xia, Ding, Kan
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.02.2022; Springer Nature B.V
• Subjects: Antibiotics; Biochemistry; Biomedical and Life Sciences; Defecation; Diarrhea; Dioscorea; Functional foods & nutraceuticals; IL-1β; Interleukin 1; Interleukin 6; Intestinal microflora; Life Sciences; Molecular weight; Original Article; Pathology; Polysaccharides; Rhizomes; Water content; Gut microbiota; Homogalacturonan; Antibiotic-associated-diarrhea; Intestinal flora regulation; Dioscorea opposita

Antibiotic-associated diarrhea (AAD) is a common side-effect of antibiotic treatment resulting from an imbalance in the colonic bacteria. The hypothesis of this study is to ask whether polysaccharide from the rhizome of Dioscorea opposita which is recorded as conventional herbs and food for diarrhea...