Evaluation of ASPM and TEF Gene Expressions as Potential Biomarkers for Bladder Cancer

• Published in: Biochemical genetics Vol. 58; no. 3; pp. 490 - 507
• Main Authors: Saleh, Amany A., Gohar, Suzy F., Hemida, Aiat Shaban, Elgharbawy, Mohamed, Soliman, Shimaa E.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.06.2020; Springer Nature B.V
• Subjects: Adult; Aged; Basic-Leucine Zipper Transcription Factors - genetics; Biochemistry; Biomarkers; Biomarkers, Tumor - genetics; Biomedical and Life Sciences; Biomedicine; Bladder; Bladder cancer; Cancer; Disease Progression; Down-Regulation - genetics; Female; Follow-Up Studies; Gene Expression; Gene Expression Regulation, Neoplastic; Genes; Genitourinary tract; Human Genetics; Humans; Kaplan-Meier Estimate; Male; Medical Microbiology; Medical prognosis; Metastases; Middle Aged; Nerve Tissue Proteins - genetics; Original Article; Prognosis; Progression-Free Survival; Sensitivity; Survival; Survival analysis; Tef gene; Tissues; Tumorigenesis; Tumors; Up-Regulation - genetics; Urinary bladder; Urinary Bladder Neoplasms - diagnosis; Urinary Bladder Neoplasms - genetics; Urinary Bladder Neoplasms - mortality; Urinary Bladder Neoplasms - pathology; Zoology; ASPM; Metastasis; TEF; Real-time PCR; Bladder cancer

Bladder cancer is one of the most predominant tumors of the genitourinary tract. In addition to pathological findings, the molecular modifications that might affect tumorigenesis and tumor outcome should be considered when treating bladder cancer. Accordingly, we aimed to investigate the expression...