The association between visceral adipocyte hypertrophy and NAFLD in subjects with different degrees of adiposity

• Published in: Hepatology international Vol. 17; no. 1; pp. 215 - 224
• Main Authors: Sun, Haixiang, Fang, Da, Wang, Hongdong, Wang, Jin, Yuan, Yue, Huang, Shanshan, Ma, Huayang, Gu, Tianwei, Bi, Yan
• Format: Journal Article
• Language: English
• Published: New Delhi Springer India 01.02.2023; Springer Nature B.V
• Subjects: Adipocytes; Adipose tissue; Adiposity; Biopsy; Body fat; Colorectal Surgery; Fasting; Fatty acids; Fatty liver; Female; Females; Hepatology; Humans; Hypertrophy; Hypertrophy - complications; Insulin; Insulin Resistance; Liver; Liver diseases; Male; Males; Medicine; Medicine & Public Health; Non-alcoholic Fatty Liver Disease - complications; Obesity; Obesity - complications; Original Article; Quartiles; Surgery; Tissue analysis; Liver biopsy; Obesity; NAFLD activity score; Adipose tissue; Visceral adipocyte hypertrophy; Adipocyte size; Histology; Non-alcoholic fatty liver disease; BMI

Objective To investigate the association between visceral adipocyte hypertrophy and the onset and development of non-alcoholic fatty liver disease (NAFLD) in subjects with different degrees of adiposity. Methods Omental adipose tissue and liver biopsies were collected from obese subjects. NAFLD was...