Cyclophosphamide bioactivation pharmacogenetics in breast cancer patients - Helsby, Nuala; Yong, Minghan; Burns, Kathryn; Findlay, Michael; Porter, David (Cancer chemotherapy and pharmacology, 2021)
Keywords: Adult; Aged; Antineoplastic Agents, Alkylating - administration & dosage; Antineoplastic Agents, Alkylating - pharmacokinetics; Antineoplastic Agents, Alkylating - pharmacology; Breast cancer; Breast Neoplasms - drug therapy; Breast Neoplasms - genetics; Cancer Research; Cyclophosphamide; Cyclophosphamide - administration & dosage; Cyclophosphamide - analogs & derivatives; Cyclophosphamide - metabolism; Cyclophosphamide - pharmacokinetics; Cyclophosphamide - pharmacology; Cytochrome P-450 CYP2B6 - genetics; Cytochrome P-450 CYP2C19 - genetics; Cytochrome P450; Dosage; Dose-Response Relationship, Drug; Female; Genetic diversity; Genotype; Genotype & phenotype; Genotypes; Humans; Medicine; Medicine & Public Health; Middle Aged; Oncology; Original Article; Patients; Pharmacogenetics; Pharmacokinetics; Pharmacology/Toxicology; Phenotypes; Polymorphism, Single Nucleotide; Single-nucleotide polymorphism; Young Adult; Pharmacogenetics; Cyclophosphamide; CYP2B6; CYP2C19