Non-invasive evaluation of the relationship between electrical and structural cardiac abnormalities in patients with myotonic dystrophy type 1

• Published in: Clinical research in cardiology Vol. 108; no. 8; pp. 857 - 867
• Main Authors: Chmielewski, Lukas, Bietenbeck, Michael, Patrascu, Alexandru, Rösch, Sabine, Sechtem, Udo, Yilmaz, Ali, Florian, Anca-Rezeda
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2019; Springer Nature B.V
• Subjects: Abnormalities; Adult; Cardiology; Cardiomyopathies - diagnosis; Cardiomyopathies - physiopathology; Cardiomyopathy; Conduction; Dystrophy; EKG; Electrocardiography; Female; Fibrillation; Flutter; Follow-Up Studies; Gadolinium; Heart Conduction System - physiopathology; Heart Ventricles - diagnostic imaging; Heart Ventricles - physiopathology; Humans; Ischemia; Magnetic resonance; Magnetic Resonance Imaging, Cine; Male; Mapping; Medicine; Medicine & Public Health; Monitoring; Myotonic dystrophy; Myotonic Dystrophy - diagnosis; Myotonic Dystrophy - physiopathology; Original Paper; Patients; Retrospective Studies; Strain analysis; Stroke Volume - physiology; Ventricle; Ventricular Function, Left - physiology; Inherited cardiomyopathy; Myotonic dystrophy; Cardiovascular magnetic resonance; Atrial fibrillation; Atrial flutter

Background Cardiac involvement in myotonic dystrophy type 1 (MD1) includes conduction disease, arrhythmias, and left-ventricular (LV) systolic dysfunction leading to an increased sudden cardiac death risk. An understanding of the interplay between electrical and structural myocardial changes could i...