Curcumin and other dietary polyphenols: potential mechanisms of metabolic actions and therapy for diabetes and obesity

• Published in: American journal of physiology: endocrinology and metabolism Vol. 314; no. 3; pp. E201 - E205
• Main Authors: Jin, Tianru, Song, Zhuolun, Weng, Jianping, Fantus, I. George
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.03.2018
• Subjects: Animal models; Animals; Body weight; Body weight gain; Curcumin; Curcumin - pharmacology; Curcumin - therapeutic use; Diabetes; Diabetes mellitus; Diabetes Mellitus - metabolism; Diabetes Mellitus - therapy; Diet; Energy Metabolism - drug effects; Humans; Insulin; Insulin Resistance - physiology; Intestinal microflora; Metabolic disorders; Metabolism; Metabolites; Microbiota; Obesity; Obesity - metabolism; Obesity - therapy; Phytotherapy - methods; Plants; Polyphenols; Polyphenols - pharmacology; Polyphenols - therapeutic use; Signal Transduction - drug effects; Therapy

Recent controversy regarding the therapeutic potential of curcumin indicates the challenges to research in this field. Here, we highlight the investigations of curcumin and other plant-derived polyphenols that demonstrate their application to metabolic diseases, in particular, obesity and diabetes....