Pharmacokinetics, Safety, and Tolerability of Selonsertib, an Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitor, Following First-in-Human Single and Multiple Ascending Doses in Healthy Subjects - Nelson, Cara H.; Etchevers, Kim; Yi, Saili; Breckenridge, David; Hepner, Mischa; Patel, Uptal; Ling, John; Mathias, Anita (Clinical pharmacokinetics, 2020)
Keywords: Apoptosis; Chemokines; Drug dosages; Food; Inflammation; Internal Medicine; Kinases; Laboratories; Ligands; Medicine; Medicine & Public Health; Original Research Article; Oxidative stress; Pharmacodynamics; Pharmacokinetics; Pharmacology/Toxicology; Pharmacotherapy; Phosphorylation; Urine; United States--US