Interaction of sugar stabilised silver nanoparticles with Momordica charantia seed lectin, a type II ribosome inactivating protein

• Published in: Glycoconjugate journal Vol. 40; no. 2; pp. 179 - 189
• Main Authors: Kenoth, Roopa, Sreekumar, Arya K, Sukanya, A., Prabu, A. Anand, Kamlekar, Ravi Kanth
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2023; Springer Nature B.V
• Subjects: Antitumor activity; Binding sites; Biochemistry; Biomedical and Life Sciences; Cancer; Carbohydrates - analysis; Cell recognition; Cell surface; Diagnosis; Drug delivery; Fluorescence spectroscopy; Galactose; Hemagglutination; Lectins; Lectins - metabolism; Life Sciences; Metal Nanoparticles; Momordica charantia; Momordica charantia - chemistry; Momordica charantia - metabolism; Nanoparticles; Nanotechnology; Original Article; Pathology; Physicochemical properties; Plant Lectins - chemistry; Plant Lectins - pharmacology; Polysaccharides; Ribosome Inactivating Proteins - analysis; Ribosome Inactivating Proteins - metabolism; Ribosome Inactivating Proteins - pharmacology; Seeds - chemistry; Silver; Silver - analysis; Silver - metabolism; Sugar; Sugars - metabolism; Tumors; Fluorescence spectroscopy; Lectin-nanoparticle interaction; Hemagglutination; Fluorescence quenching

Sugar-stabilised nanomaterials have received a lot of attention in cancer therapy in recent years due to their pronounced application as specific targeting agents and maximizing their therapeutic potential while bypassing off-target effects. Lectins, the carbohydrate-binding proteins, are capable of...