Aquaporin water channels: roles beyond renal water handling

• Published in: Nature reviews. Nephrology Vol. 19; no. 9; pp. 604 - 618
• Main Authors: Login, Frédéric H., Nejsum, Lene N.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.09.2023; Nature Publishing Group
• Subjects: 631/443; 692/4022; Aquaporins; Medicine; Medicine & Public Health; Nephrology; Physiology; Review Article; Roles

Aquaporin (AQP) water channels are pivotal to renal water handling and therefore in the regulation of body water homeostasis. However, beyond the kidney, AQPs facilitate water reabsorption and secretion in other cells and tissues, including sweat and salivary glands and the gastrointestinal tract. A...