Systemic adverse events and all-cause mortality following same-session bilateral intravitreal anti-VEGF injections: a systematic review

• Published in: Graefe's archive for clinical and experimental ophthalmology Vol. 262; no. 8; pp. 2355 - 2364
• Main Authors: Bjerager, Jakob, Hajari, Javad, Klefter, Oliver Niels, Subhi, Yousif, Schneider, Miklos
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2024; Springer Nature B.V
• Subjects: Adverse events; Angiogenesis Inhibitors - administration & dosage; Angiogenesis Inhibitors - adverse effects; Bevacizumab - administration & dosage; Bevacizumab - adverse effects; Cause of Death - trends; Humans; Incidence; Injection; Intravitreal Injections; Medicine; Medicine & Public Health; Mortality; Ophthalmology; Population studies; Registration; Review Article; Survival Rate - trends; Vascular endothelial growth factor; Vascular Endothelial Growth Factor A - antagonists & inhibitors; Visual Acuity; Intravitreal; Same-session; Same-day; Mortality; Adverse event; Bilateral; Risk; Death; Systematic review; Anti-VEGF; Injection

Purpose To review the risk of systemic adverse events and all-cause mortality following same-day bilateral anti-VEGF injections. Methods Twelve literature databases were searched for studies on same-session bilateral intravitreal anti-VEGF injections. Studies reporting on systemic adverse events and...