Evaluation of matrix metalloproteinase-1, -2, -3, -7, and -13 gene polymorphisms in patients with chronic periodontitis and healthy controls

• Published in: Clinical oral investigations Vol. 27; no. 12; pp. 7417 - 7423
• Main Authors: Saremi, Leila, Esmaeili, Saharnaz, Ghaffari, Mohammad Ebrahim, Shahbazi, Soheil, Lotfipanah, Shirin, Kadkhodazadeh, Mahdi
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2023; Springer Nature B.V
• Subjects: Alleles; Biomarkers; Collagenase 3; Dentistry; Gelatinase A; Gene frequency; Gene polymorphism; Genetic diversity; Gum disease; Interstitial collagenase; Matrilysin; Matrix metalloproteinase; Medicine; Metalloproteinase; Nucleotide sequence; Oral hygiene; Periodontics; Periodontitis; Polymerase chain reaction; Population studies; Restriction fragment length polymorphism; Statistical analysis; Stromelysin 1; Genotype; Chronic Periodontitis; DNA; Matrix Metalloproteinases; Alleles; Polymorphism

Objectives The current study aimed to investigate the association of matrix metalloproteinase- (MMP-) 1, -2, -3, -7, and -13 gene polymorphisms with chronic periodontitis (CP) in an Iranian population. Materials and Methods In this case–control study, 87 subjects with CP and 89 periodontally healthy...