Safety, Tolerability and Pharmacokinetics of Single Ascending and Multiple Oral Doses of Tegoprazan in Healthy Chinese Subjects - He, Jinjie; Cao, Guoying; Yu, Jicheng; Wang, Jingjing; Cheng, Nengneng; Wu, Jufang; Zhang, Jing; Wu, Xiaojie; Zhang, Basheng; Lu, Jiayan; Chen, Shangzhi (Clinical drug investigation, 2021)
Keywords: Adenosine triphosphatase; Administration, Oral; Adult; Area Under Curve; Asian Continental Ancestry Group; Benzene Derivatives - administration & dosage; Benzene Derivatives - adverse effects; Benzene Derivatives - pharmacokinetics; Blood & organ donations; Chromatography; Chromatography, Liquid; Double-Blind Method; Drug dosages; Electrocardiography; Female; Gastroesophageal reflux; Hepatitis; Humans; Imidazoles - administration & dosage; Imidazoles - adverse effects; Imidazoles - pharmacokinetics; Internal Medicine; Male; Mass spectrometry; Medical laboratories; Medicine; Medicine & Public Health; Original Research Article; Pharmacokinetics; Pharmacology/Toxicology; Pharmacotherapy; Plasma; Potassium; Scientific imaging; Tandem Mass Spectrometry; Ulcers; Vital signs; Young Adult; China