Cholesterol Induces Epithelial-to-Mesenchymal Transition of Prostate Cancer Cells by Suppressing Degradation of EGFR through APMAP - Jiang, Siyuan; Wang, Xuetong; Song, Dalong; Liu, XiaoJun; Gu, Yinmin; Xu, Zhiyuan; Wang, Xiaodong; Zhang, Xiaolu; Ye, Qinong; Tong, Zhou; Yan, BingXue; Yu, Jie; et al. (Cancer research (Chicago, Ill.), 2019)
Keywords: Adaptor Proteins, Signal Transducing - genetics; Adaptor Proteins, Signal Transducing - metabolism; Animals; Apoptosis; Case-Control Studies; Cell Proliferation; Cholesterol - pharmacology; Epithelial-Mesenchymal Transition - drug effects; ErbB Receptors - genetics; ErbB Receptors - metabolism; Gene Expression Regulation, Neoplastic - drug effects; Humans; Male; Membrane Glycoproteins - genetics; Membrane Glycoproteins - metabolism; Mice; Mice, Inbred NOD; Mice, SCID; Prognosis; Prostatic Neoplasms - drug therapy; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; Proteolysis - drug effects; Tumor Cells, Cultured; Xenograft Model Antitumor Assays