The role of NK cells in rheumatoid arthritis

• Published in: Inflammation research Vol. 70; no. 10-12; pp. 1063 - 1073
• Main Authors: Fathollahi, Anwar, Samimi, Leila Nejatbakhsh, Akhlaghi, Maassoumeh, Jamshidi, Ahmadreza, Mahmoudi, Mahdi, Farhadi, Elham
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.12.2021; Springer Nature B.V
• Subjects: Absorptivity; Allergology; Animals; Arthritis; Arthritis, Rheumatoid - immunology; Biomedical and Life Sciences; Biomedical materials; Biomedicine; Cytotoxicity; Dermatology; Humans; Immune response; Immune system; Immunology; Immunopathogenesis; Innate immunity; Killer Cells, Natural - immunology; Literature reviews; Natural killer cells; Neurology; Osteoclasts; Osteoclasts - immunology; Pathogenesis; Perforin; Peripheral blood; Pharmacology/Toxicology; Receptors, Natural Killer Cell - immunology; Review; Rheumatoid arthritis; Rheumatology; Osteoclasts; Natural killer cells; Pathogenesis; Rheumatoid arthritis; NK cell subsets

Objective Natural killer (NK) cells are part of the innate immune system which not only provides a primary response to pathogenic conditions but can also play an important regulatory role in immune responses. Furthermore, these cells can influence immune responses by affecting other involved cells....