Extramedullary plasmacytoma of the larynx

Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm that occurs in the soft tissues, especially in the upper airways. We report two cases of laryngeal EMP, both of which were treated by surgical resection, one with and one without combination radiotherapy. A 39-year-old male was diagnos...

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Published inAuris, nasus, larynx Vol. 33; no. 2; pp. 219 - 222
Main Authors Nakashima, Takahiro, Matsuda, Keiji, Haruta, Atsushi
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ireland Ltd 01.06.2006
Subjects
Adult
Cell Proliferation
Combined Modality Therapy
Disease-Free Survival
Extramedullary plasmacytoma
Humans
Laryngeal Neoplasms - pathology
Laryngeal Neoplasms - radiotherapy
Laryngeal Neoplasms - surgery
Laryngoscopy
Larynx
Male
Middle Aged
Neoplasm Staging
Plasmacytoma - pathology
Plasmacytoma - radiotherapy
Plasmacytoma - surgery
Radiotherapy
Treatment Outcome
Radiotherapy
Extramedullary plasmacytoma
Larynx
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Abstract Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm that occurs in the soft tissues, especially in the upper airways. We report two cases of laryngeal EMP, both of which were treated by surgical resection, one with and one without combination radiotherapy. A 39-year-old male was diagnosed with a laryngeal tumor localized in the left arytenoid region in October 1999. Biopsy showed the tumor to be a plasmacytoma. He underwent a direct laryngoscopy and resection of the tumor with a KTP laser. Consequently, he received radiotherapy to a total dose of 60 Gy. He has remained clear, with no local recurrence during 6 years of follow-up. A 59-year-old male was diagnosed with an epiglottic tumor in December 1989. He underwent a direct laryngoscopy and removal of the tumor. Histopathological study of the tumor showed a diffuse proliferation of plasmacytoid cells. He has remained diseasefree during 15 years of follow-up.
AbstractList Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm that occurs in the soft tissues, especially in the upper airways. We report two cases of laryngeal EMP, both of which were treated by surgical resection, one with and one without combination radiotherapy. A 39-year-old male was diagnosed with a laryngeal tumor localized in the left arytenoid region in October 1999. Biopsy showed the tumor to be a plasmacytoma. He underwent a direct laryngoscopy and resection of the tumor with a KTP laser. Consequently, he received radiotherapy to a total dose of 60 Gy. He has remained clear, with no local recurrence during 6 years of follow-up. A 59-year-old male was diagnosed with an epiglottic tumor in December 1989. He underwent a direct laryngoscopy and removal of the tumor. Histopathological study of the tumor showed a diffuse proliferation of plasmacytoid cells. He has remained diseasefree during 15 years of follow-up.
Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm that occurs in the soft tissues, especially in the upper airways. We report two cases of laryngeal EMP, both of which were treated by surgical resection, one with and one without combination radiotherapy. A 39-year-old male was diagnosed with a laryngeal tumor localized in the left arytenoid region in October 1999. Biopsy showed the tumor to be a plasmacytoma. He underwent a direct laryngoscopy and resection of the tumor with a KTP laser. Consequently, he received radiotherapy to a total dose of 60 Gy. He has remained clear, with no local recurrence during 6 years of follow-up. A 59-year-old male was diagnosed with an epiglottic tumor in December 1989. He underwent a direct laryngoscopy and removal of the tumor. Histopathological study of the tumor showed a diffuse proliferation of plasmacytoid cells. He has remained diseasefree during 15 years of follow-up.
Author Matsuda, Keiji
Haruta, Atsushi
Nakashima, Takahiro
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Extramedullary plasmacytoma
Larynx
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Snippet Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm that occurs in the soft tissues, especially in the upper airways. We report two cases of...
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SubjectTerms Adult
Cell Proliferation
Combined Modality Therapy
Disease-Free Survival
Extramedullary plasmacytoma
Humans
Laryngeal Neoplasms - pathology
Laryngeal Neoplasms - radiotherapy
Laryngeal Neoplasms - surgery
Laryngoscopy
Larynx
Male
Middle Aged
Neoplasm Staging
Plasmacytoma - pathology
Plasmacytoma - radiotherapy
Plasmacytoma - surgery
Radiotherapy
Treatment Outcome
Title Extramedullary plasmacytoma of the larynx
URI https://dx.doi.org/10.1016/j.anl.2005.11.019
https://www.ncbi.nlm.nih.gov/pubmed/16406428
https://search.proquest.com/docview/67947218
Volume 33
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