Bioengineering strategies for restoring vision

• Published in: Nature biomedical engineering Vol. 7; no. 4; pp. 387 - 404
• Main Authors: Cehajic-Kapetanovic, Jasmina, Singh, Mandeep S., Zrenner, Eberhart, MacLaren, Robert E.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.04.2023; Nature Publishing Group
• Subjects: 42; 42/100; 42/41; 631/532; 631/532/489; 631/61; 631/61/201; 631/61/2320; Age; Age related diseases; Bioengineering; Biomedical and Life Sciences; Biomedical Engineering/Biotechnology; Biomedicine; Cell Transplantation; Degenerative diseases; Eye diseases; Gene therapy; Genetic modification; Humans; Macular degeneration; Neural prostheses; Photoreceptors; Prostheses; Prosthetics; Restoration; Retina; Retinal degeneration; Retinal Degeneration - surgery; Review Article; Transplantation; Vision; Vision, Ocular; Visual perception

Late-stage retinal degenerative disease involving photoreceptor loss can be treated by optogenetic therapy, cell transplantation and retinal prostheses. These approaches aim to restore light sensitivity to the retina as well as visual perception by integrating neuronal responses for transmission to...