Quantitative susceptibility atlas construction in Montreal Neurological Institute space: towards histological-consistent iron-rich deep brain nucleus subregion identification

• Published in: Brain Structure and Function Vol. 228; no. 5; pp. 1045 - 1067
• Main Authors: He, Chenyu, Guan, Xiaojun, Zhang, Weimin, Li, Jun, Liu, Chunlei, Wei, Hongjiang, Xu, Xiaojun, Zhang, Yuyao
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2023; Springer Nature B.V
• Subjects: Biomedical and Life Sciences; Biomedicine; Brain; Brain - diagnostic imaging; Brain - pathology; Brain Mapping - methods; Cell Biology; Cognitive ability; Deep brain stimulation; Gray Matter - diagnostic imaging; Humans; Image processing; Iron; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Magnetic susceptibility; Mental disorders; Movement disorders; Neurodegenerative diseases; Neuroimaging; Neurology; Neurosciences; Original Article; Parkinson's disease; Pathology; Segmentation; Spatial distribution; Susceptibility; Thalamus; Canada; Montreal Quebec Canada; Quantitative susceptibility atlas; Deep brain nuclei; Basal ganglia; Parcellation; Multi-modal atlases; Thalamus; Quantitative susceptibility mapping

Iron-rich deep brain nuclei (DBN) of the human brain are involved in various motoric, emotional and cognitive brain functions. The abnormal iron alterations in the DBN are closely associated with multiple neurological and psychiatric diseases. Quantitative susceptibility mapping (QSM) provides the s...