Increased plasma levels of CCL20 in peripheral blood of rheumatoid arthritis patients and its association with clinical and laboratory parameters

• Published in: Clinical rheumatology Vol. 41; no. 1; pp. 265 - 270
• Main Authors: Pournazari, Mehran, Feizollahi, Parisa, Roghani, Seyed Askar, Assar, Shirin, Soufivand, Parviz, Soleymani, Bijan, Bahrehmand, Fariborz, Kish, Zahra Mohammadi, Taghadosi, Mahdi
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 2022; Springer Nature B.V
• Subjects: Arthritis, Rheumatoid; Autoantibodies; Autoimmune diseases; Biomarkers; CCL20 protein; Chemokine CCL20; Chemokines; Citrulline; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Joint diseases; Laboratories; Medicine; Medicine & Public Health; Original Article; Pathogenesis; Patients; Peptides, Cyclic; Peripheral blood; Plasma; Plasma levels; Rheumatoid arthritis; Rheumatoid Factor; Rheumatology; DAS28; RF; Anti-CCP; CCL20; Rheumatoid arthritis; Chemokines

Introduction Rheumatoid arthritis (RA) is a systemic autoimmune disease that primarily affects small joints. The impaired chemokine and cytokine responses are essential pathological mechanisms for the RA clinical presentation. Given the role of chemokines and inflammatory reactions in RA pathogenesi...