MicroRNA-mediated regulation of BM-MSCs differentiation into sweat gland-like cells: targeting NF-κB

• Published in: Journal of molecular histology Vol. 50; no. 2; pp. 155 - 166
• Main Authors: Chen, Yan, Li, Qiankun, Tan, Zhijun, Zhang, Cuiping, Fu, Xiaobing
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.04.2019; Springer Nature B.V
• Subjects: Bioinformatics; Biomedical and Life Sciences; Biomedicine; Bone marrow; Burn patients; Cell Biology; Cell culture; Developmental Biology; Life Sciences; Mesenchyme; miRNA; NF-κB protein; Original Paper; Regeneration; Skin; Stem cells; Sweat; Sweat gland; Sweat gland; NF-κB; MicroRNA; Differentiation; BM-MSCs

Sweat gland regeneration is important for patients with an extensive deep burn injury. In previous study, we reported that bone marrow-mesenchymal stem cells (BM-MSCs) could differentiate into sweat gland-like cells (SGLCs), but the underlying molecular mechanism remains unclear. Recently, microRNAs...