Safety and Pharmacokinetics of HRS-2261, a P2X3 Receptor Antagonist, in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study - Fan, Yuru; Zhang, Xuan; Zhang, Qin; Zheng, Liang; Zhou, Renpeng; Sun, Cheng; Wang, Xihan; Song, Ke; He, Zhusheng; Wang, Honghui; Zhang, Qian; Hu, Wei (Clinical pharmacokinetics, 2024)
Keywords: Adenosine triphosphate; Area Under Curve; Clinical trials; Dose-Response Relationship, Drug; Double-Blind Method; Drug dosages; Dysgeusia; Healthy Volunteers; Hepatitis; Humans; Internal Medicine; Male; Medicine; Medicine & Public Health; NCT; NCT05274516; Original Research Article; Pharmacokinetics; Pharmacology/Toxicology; Pharmacotherapy; Purinergic P2X Receptor Antagonists - adverse effects; Taste disorders; United States--US