Mannose-specific plant and microbial lectins as antiviral agents: A review

• Published in: Glycoconjugate journal Vol. 41; no. 1; pp. 1 - 33
• Main Authors: Gupta, Ankita, Yadav, Kusum, Yadav, Anurag, Ahmad, Rumana, Srivastava, Aditi, Kumar, Dileep, Khan, Mohammad Amir, Dwivedi, U. N.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.02.2024; Springer Nature B.V
• Subjects: Antiviral activity; Antiviral agents; Antiviral Agents - chemistry; Antiviral Agents - pharmacology; Antiviral Agents - therapeutic use; Antiviral drugs; Biochemistry; Biomedical and Life Sciences; Biopharmaceuticals; Coronaviruses; Glycoproteins; Hepatitis; HIV; Human immunodeficiency virus; Humans; Lectins; Lectins - metabolism; Life cycles; Life Sciences; Mannose; Mannose-Binding Lectins - chemistry; N-glycans; Pathology; Plant Lectins - pharmacology; Polysaccharides; Review; SARS-CoV-2; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Therapeutic applications; Virus attachment; Virus Diseases - drug therapy; Antiviral agents; Mannose-specific lectins; Viruses; Plant lectins

Lectins are non-immunological carbohydrate-binding proteins classified on the basis of their structure, origin, and sugar specificity. The binding specificity of such proteins with the surface glycan moiety determines their activity and clinical applications. Thus, lectins hold great potential as di...