Abnormal paravertebral muscles development is associated with abnormal expression of PAX3 in adolescent idiopathic scoliosis

• Published in: European spine journal Vol. 29; no. 4; pp. 737 - 743
• Main Authors: Qin, Xiaodong, He, Zhong, Yin, Rui, Qiu, Yong, Zhu, Zezhang
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.04.2020; Springer Nature B.V
• Subjects: Adolescent; Humans; Intervertebral discs; Kyphosis; Magnetic Resonance Imaging; Medicine; Medicine & Public Health; Muscle, Skeletal - diagnostic imaging; Muscles; Neurosurgery; Original Article; Pax3 protein; PAX3 Transcription Factor - genetics; Scoliosis; Scoliosis - diagnostic imaging; Spine; Spine (lumbar); Surgical Orthopedics; Vertebrae; Etiology; Paravertebral muscle; Adolescent idiopathic scoliosis; PAX3

Purpose The study is aimed to investigate the expression of PAX3 in bilateral paravertebral muscles in adolescent idiopathic scoliosis (AIS) and controls, and to further clarify its association with the paravertebral muscle volume and curve severity. Methods Ten AIS patients and 10 age-matched contr...