Combined gadoxetic acid and gadobenate dimeglumine enhanced liver MRI: a parameter optimization study

• Published in: Abdominal imaging Vol. 45; no. 1; pp. 220 - 231
• Main Authors: Knobloch, Gesine, Colgan, Timothy, Wang, Xiaoke, Woo, Kaitlin M., Schubert, Tilman, Reeder, Scott B.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.01.2020; Springer Nature B.V
• Subjects: Adult; Contrast agents; Contrast Media; Experiments; Feasibility; Feasibility Studies; Female; Gadolinium DTPA; Gastroenterology; Hepatobiliary; Hepatology; Humans; Image contrast; Image Enhancement - methods; Imaging; Liver; Liver - anatomy & histology; Liver diseases; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Medical imaging; Medicine; Medicine & Public Health; Meglumine - analogs & derivatives; Metastases; Metastasis; Muscles; Optimization; Organometallic Compounds; Prospective Studies; Radiology; Reference Values; Signal to noise ratio; Liver diseases; Magnetic resonance imaging; Gadobenic acid; Contrast media; Gadolinium ethoxybenzyl DTPA

Purpose To demonstrate the feasibility of combined delayed-phase gadoxetic acid (GA) and gadobenate dimeglumine (GD) enhanced liver MRI for improved detection of liver metastases, and to optimize contrast agent dose, timing, and flip angle (FA). Methods Fourteen healthy volunteers underwent liver MR...