Fuchs endothelial corneal dystrophy: an updated review

• Published in: International ophthalmology Vol. 44; no. 1; p. 61
• Main Authors: Altamirano, Francisco, Ortiz-Morales, Gustavo, O’Connor-Cordova, Mario A., Sancén-Herrera, Juan Pablo, Zavala, Judith, Valdez-Garcia, Jorge E.
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 12.02.2024; Springer Nature B.V
• Subjects: Acuity; Age; Blindness; Cornea; Corneal dystrophy; Corneal Transplantation; Diagnosis; Dystrophy; Endothelial Cells; Endothelium; Endothelium, Corneal; Fuchs' Endothelial Dystrophy - diagnosis; Fuchs' Endothelial Dystrophy - genetics; Fuchs' Endothelial Dystrophy - therapy; Genes; Humans; Literature reviews; Medicine; Medicine & Public Health; Ophthalmology; Pathophysiology; Review; Transplants; Visual acuity; Eye; Fuchs’ endothelial corneal dystrophy; Genetics; Corneal dystrophy; Rho kinase inhibitors

Purpose The present review will summarize FECD-associated genes and pathophysiology, diagnosis, current  therapeutic approaches, and future treatment perspectives. Methods Literature review. Results Fuchs' endothelial corneal dystrophy (FECD) is the most common bilateral corneal dystrophy and a...