Nasopharyngeal carcinoma treated with intensity-modulated radiotherapy: clinical outcomes and patterns of failure among subsets of 8th AJCC stage IVa

• Published in: European radiology Vol. 30; no. 2; pp. 816 - 822
• Main Authors: Huang, Cheng-Long, Guo, Rui, Li, Jun-Yan, Xu, Cheng, Mao, Yan-Ping, Tian, Li, Lin, Ai-Hua, Sun, Ying, Ma, Jun, Tang, Ling-long
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2020; Springer Nature B.V
• Subjects: Adult; Aged; Cancer; Clinical outcomes; Confidence intervals; Diagnostic Radiology; Female; Follow-Up Studies; Head and Neck; Humans; Imaging; Internal Medicine; Interventional Radiology; Kaplan-Meier Estimate; Male; Medical prognosis; Medicine; Medicine & Public Health; Metastases; Metastasis; Middle Aged; Multivariate analysis; Nasopharyngeal carcinoma; Nasopharyngeal Carcinoma - pathology; Nasopharyngeal Carcinoma - radiotherapy; Nasopharyngeal Carcinoma - secondary; Nasopharyngeal Neoplasms - pathology; Nasopharyngeal Neoplasms - radiotherapy; Neoplasm Recurrence, Local - pathology; Neoplasm Staging; Neuroradiology; Prognosis; Radiation therapy; Radiology; Radiotherapy, Intensity-Modulated - methods; Retrospective Studies; Survival; Throat cancer; Treatment Failure; Treatment Outcome; Ultrasound; Nasopharyngeal carcinoma; Treatment failure; Stage; Intensity-modulated radiotherapy; Prognosis

Objectives The 8th edition of the American Joint Committee on Cancer (AJCC) staging system for nasopharyngeal carcinoma (NPC) merged T4N0–2 and T1–4N3 to create stage IVa. In the present study, we aimed to assess the difference in clinical outcomes and patterns of failure between 8th AJCC T4N0–2 and...