Combinatorial Photothermal 3D‐Printing Scaffold and Checkpoint Blockade Inhibits Growth/Metastasis of Breast Cancer to Bone and Accelerates Osteogenesis

• Published in: Advanced functional materials Vol. 31; no. 10
• Main Authors: He, Chao, Yu, Luodan, Yao, Heliang, Chen, Yu, Hao, Yongqiang
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.03.2021
• Subjects: Biodegradability; Biomedical materials; bone metastasis, breast cancer; Breast cancer; checkpoint blockade; Combinatorial analysis; Design optimization; Genomes; Immune system; Immunology; Immunotherapy; Materials science; Metastasis; Niobium carbide; osteogenesis; photothermal therapy; Regeneration; Scaffolds; Three dimensional printing; Tissue engineering; Tumors

Cancer metastases are the main causes for the high mortality of cancer. The current treatment modality for bone metastasis of breast cancer is dominantly destructive, which urges the engineering of multifunctional biomaterials, not only for eliminating primary/metastases tumors effectively but also...