Ondansetron is not superior to moderate dose metoclopramide in the prevention of post-operative nausea and vomiting after minor gynaecological surgery

• Published in: European journal of anaesthesiology Vol. 14; no. 6; p. 604
• Main Authors: Monagle, J, Barnes, R, Goodchild, C, Hewitt, M
• Format: Journal Article
• Language: English
• Published: England 01.11.1997
• Subjects: Adult; Antiemetics - adverse effects; Antiemetics - therapeutic use; Dilatation and Curettage; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Laparoscopy; Metoclopramide - adverse effects; Metoclopramide - therapeutic use; Nausea - prevention & control; Ondansetron - adverse effects; Ondansetron - therapeutic use; Postoperative Complications - prevention & control; Pregnancy; Prospective Studies; Vomiting - prevention & control

Peri-operative nausea and vomiting (PONV), remain a considerable problem. Ondansetron is being promoted currently as the drug of choice for the prevention and treatment of PONV. Experiments to investigate efficacy of ondansetron in PONV have been made with placebo or single doses of other drugs, e.g...