Metabolic syndrome as independent risk factor among sample of Egyptian women with breast cancer

• Published in: Bulletin of the National Research Centre Vol. 46; no. 1; pp. 1 - 9
• Main Authors: Mahmoud, Walaa S., Azmy, Osama M., Abu-Elghait, Mohammed, Gomaa, Mohammed Mohammed Mohammed, El Sayed, Ibrahim El Tantawy, Hammad, Doaa Y., Kamel, Mahmoud M., Abdelqader, Eslam M., Yousef, Walaa
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2022; Springer Nature B.V; SpringerOpen
• Subjects: Anthropometric indices; Anthropometry; Body measurements; Body weight; Breast cancer; Health risks; Hip; Humanities and Social Sciences; Medicine and Human Genetics; Metabolic disorders; Metabolic syndrome; multidisciplinary; Overweight; Risk analysis; Risk factors; Science; Science (multidisciplinary); Metabolic syndrome; Anthropometric indices; Breast cancer
• ISSN: 2522-8307; 2522-8307
• DOI: 10.1186/s42269-022-00962-2

Background Metabolic syndrome (MetS) and breast cancer (BC) are closely related and need more clarification. In clinical practice, the early diagnosis of BC is the most crucial issue. The current study aimed to investigate the incidence of metabolic syndrome among Egyptian women with breast cancer as independent risk factor, and the relationships between anthropometric indices (BMI, waist, hip, middle upper arm circumferences) and breast cancer risk. Results MetS rate was significantly higher among women with breast cancer ( n  = 89, 65%) women; compared to CG: 43.5%, (37) women therefore metabolic syndrome was strongly associated with breast cancer. More than half of BC cases ( n  = 85, 62%) were obese (BMI > 29.9), and 37 women (27%) were overweight (BMI 25–29.9). Additionally, the BC group had greater levels of fasting blood sugar than the control group (109.72 ± 51.31, 78.49 ± 22.79 mg/dL, respectively). Waist circumference, hip circumference, and WHtR values in BC women showed highly significant difference ( p value = 0.000) compared to control group. Conclusion In our study, the metabolic syndrome and its elements were significantly correlated among Egyptian women with breast cancer. Anthropometric indices were linked to an increased risk of breast cancer.