Time delay during intra-base proton tunneling in the guanine base of the single stranded DNA

• Published in: Progress in biophysics and molecular biology Vol. 173; pp. 4 - 10
• Main Authors: Özçelik, Elif, Akar, Demet Eda, Zaman, Semih, Demir, Durmuş
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.09.2022
• Subjects: Entropic tunneling time; Intra-base proton tunneling; Single stranded DNA; Entropic tunneling time; Single stranded DNA; Intra-base proton tunneling

Spontaneous point mutations are one of the main actors in evolution, and the tautomerization of organic bases in the DNA is hypothesized to be the underlying mechanism of this crucial process. Tautomerization can be induced by proton tunneling, and if it occurs in single-stranded DNA (ssDNA) during...