Radiosynthesis of [ 18 F]brequinar for in vivo PET imaging of hDHODH for potential studies of acute myeloid leukemia and cancers - Banka, Vinay Kumar; Sainas, Stefano; Martino, Elena; Wang, Jiacheng; Lolli, Marco Lucio; Ding, Yu-Shin (MedChemComm, 2024)
Keywords: Acute myeloid leukemia; Autoimmune diseases; Biochemistry & Molecular Biology; Biosynthesis; Cancer; Chemistry; Chemistry, Medicinal; Clinical trials; Dihydroorotate dehydrogenase; Drug development; Fluorine isotopes; Health services; In vivo methods and tests; Leukemia; Life Sciences & Biomedicine; Medical imaging; Medical treatment; Pharmacology & Pharmacy; Positron emission; Precision medicine; Radioactive tracers; Radiolabelling; Science & Technology; DESIGN; ACID; RADIOFLUORINATION; SCAFFOLD SAR; MEDIATED F-18-FLUORINATION; DHODH INHIBITORS; DIFFERENTIATION; FLUORINATION; DIHYDROOROTATE